176 Participants NeededMy employer runs this trial

Cannabis Use Reduction Program for Cannabis Use Disorder

RT
EM
Overseen ByErin McClure, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Medical University of South Carolina
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help individuals reduce cannabis use if they have cannabis use disorder (CUD). The study combines motivational interviewing, online therapy sessions (Computerized Cognitive Behavioral Therapy, or CBT4CBT), and rewards to determine if these methods enhance sleep, mental focus, and overall quality of life. Ideal participants have been diagnosed with CUD, are willing to reduce their cannabis use, and have high levels of cannabis in their systems. The research seeks to find better ways to manage and improve the lives of those struggling with CUD. As an unphased trial, it offers participants the chance to contribute to innovative research that could lead to new strategies for managing CUD.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It mainly focuses on reducing cannabis use.

What prior data suggests that this program is safe for participants?

Research has shown that both computerized cognitive behavioral therapy (CBT4CBT) and motivational interviewing are generally safe and well-tolerated by participants. Studies have found that CBT4CBT effectively treats cannabis use disorder without causing major side effects and is often used alongside standard care.

Motivational interviewing has also undergone extensive study. Research indicates it can help individuals stop using cannabis, with no significant reports of negative effects when treating cannabis use disorder. Overall, research supports both treatments as safe options for reducing cannabis use.12345

Why are researchers excited about this trial?

Researchers are excited about the Cannabis Use Reduction Program because it combines Computerized Cognitive Behavioral Therapy (CBT4CBT) and Motivational Interviewing to tackle Cannabis Use Disorder in a unique way. Unlike traditional therapies that often require in-person sessions, CBT4CBT is delivered digitally, offering flexibility and accessibility for users. This method allows individuals to engage with therapy on their own schedule, potentially increasing adherence and effectiveness. Additionally, Motivational Interviewing adds a personalized touch by helping individuals find their internal motivation to reduce cannabis use, which is not always a focus of standard treatments. Together, these approaches aim to provide a more tailored and accessible solution for those struggling with cannabis use.

What evidence suggests that this trial's treatments could be effective for cannabis use disorder?

Studies have shown that both computerized cognitive behavioral therapy (CBT4CBT) and motivational interviewing can help reduce cannabis use in people with cannabis use disorder (CUD). In this trial, participants may receive either CBT4CBT or motivational interviewing. Research indicates that CBT4CBT can significantly lower cannabis use and improve mental health symptoms. Motivational interviewing has been linked to fewer days of cannabis use and a reduced amount used. These treatments help people change their thoughts and behaviors regarding cannabis use. Both methods have shown promise in helping people cut back on cannabis, leading to better overall health and quality of life.12567

Who Is on the Research Team?

RT

Rachel Tomko, PhD.

Principal Investigator

Medical University of South Carolina

EM

Erin McClure, PhD.

Principal Investigator

Medical University of South Carolina

Are You a Good Fit for This Trial?

This trial is for adults age 18 or older who have been diagnosed with cannabis use disorder, have a certain level of cannabis in their urine, and are willing to try reducing their cannabis use.

Inclusion Criteria

My urine test for cannabinoids is 50 ng/mL or higher.
I am 18 years old or older.
I have been diagnosed with a Cannabis Use Disorder.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids

8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Computerized Cognitive Behavioral Therapy (CBT4CBT)
  • Financial Incentives
  • Motivational Interviewing

Trial Overview

The study tests an 8-week program that combines motivational interviewing, online cognitive behavioral therapy (CBT4CBT), and financial rewards to help people reduce cannabis use. Researchers will look at changes in health, sleep, thinking skills, and quality of life.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Medical University of South Carolina

Lead Sponsor

Trials
994
Recruited
7,408,000+

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

Citations

An Initial Trial of a Computerized Behavioral Intervention for ...

Attendance, retention, and cannabis use outcomes did not differ significantly between groups, and there were no indications of superior outcomes favoring ...

Effectiveness of cognitive behavioral therapy for harmful ...

Meta-analysis results showed that CBT didn't produce significant reductions in cannabis use frequency, compared with contingency management, treatment as usual ...

Effectiveness and clinical predictors of a virtual based ...

Conclusion. Virtual CBT-MET was feasible and led to significant reductions in cannabis use and psychiatric symptoms among individuals with CUD.

Computer Based Treatment for Cognitive Behavioral ...

The authors of this systematic review conclude that these results show that digital interventions can be effective in opioid use disorder and ...

Effectiveness of cannabis use and cannabis use disorder ...

Pooled analyses indicated that self-reported cannabis use was reduced significantly post digital intervention. The strongest treatment effects ...

Cognitive Behavioural Therapy for Cannabis Use Disorder

Research has shown that cognitive behavioral therapy (CBT), including CBT4CBT, is generally safe and well-tolerated by participants. Studies have found that ...

Cognitive behavioral therapy for comorbid cannabis use ...

Individuals with cannabis misuse and/or CUD experience especially high rates of anxiety and depressive disorders (ie, emotional disorders).