Proton Radiation Therapy for Brain Tumor
Trial Summary
What is the purpose of this trial?
This research study is studying Proton Radiation as a possible treatment for brain tumor. The radiation involved in this study is: -Proton Radiation
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
What data supports the effectiveness of the treatment Proton Radiation Therapy for Brain Tumor?
Proton radiation therapy is shown to be effective in treating brain tumors by minimizing damage to surrounding healthy tissues, which can help reduce side effects and improve quality of life. Studies have demonstrated its benefits in reducing neurocognitive decline and the risk of secondary cancers compared to traditional radiation methods.12345
Is proton radiation therapy generally safe for humans?
How is proton radiation therapy different from other treatments for brain tumors?
Proton radiation therapy is unique because it uses protons to deliver radiation directly to the tumor, minimizing damage to surrounding healthy tissues. This precision reduces the risk of side effects like neurocognitive decline and secondary cancers, making it especially beneficial for treating brain tumors near sensitive areas.24101112
Research Team
Helen A Shih, MD
Principal Investigator
Massachusetts General Hospital
Eligibility Criteria
Adults over 18 with benign or low-grade brain tumors who need radiation therapy can join this trial. They must be able to understand English, sign consent, use contraception if needed, and have a life expectancy of at least 6 months. People with severe illnesses, heart problems, psychiatric conditions that affect compliance, or pregnant/lactating women cannot participate.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants receive Proton Radiation therapy, typically five days per week on weekdays
Follow-up
Participants are monitored for safety, effectiveness, and quality of life changes after treatment
Long-term follow-up
Participants are monitored for long-term effects and tumor response up to 5 years post-treatment
Treatment Details
Interventions
- Proton Radiation
Proton Radiation is already approved in United States, European Union, Canada, Japan for the following indications:
- Brain tumors
- Breast cancer
- Esophageal cancer
- Eye cancer
- Gynecological cancers
- Head and neck cancer
- Liver cancer
- Lung cancer
- Lymphoma
- Pancreatic cancer
- Prostate cancer
- Rectal cancer
- Sarcomas
- Spinal cord tumors
- Similar indications as in the United States, with specific approvals varying by country
- Similar indications as in the United States, with specific approvals varying by province
- Similar indications as in the United States, with specific approvals varying by region
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor