CT Perfusion Imaging for Subarachnoid Hemorrhage
(CT-PIPS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Patients with brain hemorrhage resulting from a ruptured aneurysm (SAH) are at risk of developing a condition called vasospasm, one or two weeks after their hemorrhage. This is a major cause of stroke and death following SAH. A special type of CT scan, called CT perfusion, analyzes regional blood flow in the brain. We hypothesize that CT perfusion scans performed on admission and day 6 post-hemorrhage will enable us to predict which patients will go on to develop vasospasm.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is CT perfusion imaging safe for humans?
How is CT Perfusion Imaging different from other treatments for subarachnoid hemorrhage?
CT Perfusion Imaging is unique because it provides a rapid and detailed assessment of blood flow in the brain, helping to detect early changes and predict complications like vasospasm and delayed cerebral ischemia, which are critical in managing subarachnoid hemorrhage. Unlike other treatments, it uses advanced imaging to guide decisions rather than directly treating the condition.12367
What data supports the effectiveness of the treatment CT Perfusion Imaging for Subarachnoid Hemorrhage?
Who Is on the Research Team?
Gwynedd E Pickett, MD
Principal Investigator
Capital District Health Authority, Halifax, Canada
Are You a Good Fit for This Trial?
This trial is for individuals aged 18-75 who have had a brain hemorrhage due to a ruptured aneurysm and can consent to participate. They must be able to attend follow-up visits and not be in another study, pregnant, breastfeeding, or expected to pass away within 24 hours.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
CT perfusion imaging performed on admission to measure cerebral blood flow and other parameters
Monitoring
CT perfusion imaging on day 6 post-hemorrhage to assess risk of vasospasm and delayed cerebral ischemia
Follow-up
Participants are monitored for safety and effectiveness after initial assessments, including radiation dose and delayed cerebral ischemia
What Are the Treatments Tested in This Trial?
Interventions
- CT Perfusion
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nova Scotia Health Authority
Lead Sponsor
Gwynedd Pickett
Lead Sponsor