Treatment for Kidney Stones

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Chicago Medical Center, Chicago, IL
Kidney Stones+3 More
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is investigating how two compounds in food, oxalate and citrate, may affect kidney stone formation. Subjects will eat special diets for 5 days and then come in for testing at the University of Chicago. This treatment is not a placebo and is used to specifically target and treat Kidney Stones.

Eligible Conditions

  • Kidney Stones
  • Bypass, Gastric
  • Bariatric Surgery

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Kidney Stones

Study Objectives

3 Primary · 3 Secondary · Reporting Duration: 6 hours

6 hours
Change in concentration of urine citrate from baseline to 2-hours, 4-hours, and 6-hours after sodium oxalate consumption.
Change in concentration of urine oxalate from baseline to 2-hours, 4-hours, and 6-hours after sodium oxalate consumption
Change in fractional excretions of citrate and oxalate from baseline to 2-hours, 4-hours, and 6-hours after sodium oxalate consumption.
Difference in change in concentration of urine citrate from baseline between kidney stone patients and controls.
Difference in change in concentration of urine oxalate from baseline between kidney stone patients and controls.
Difference in change in fractional excretions of citrate and oxalate from baseline between kidney stone patients and controls.

Trial Safety

Safety Progress

1 of 3

Other trials for Kidney Stones

Trial Design

0 Treatment Group

24 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · N/A

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 6 hours
Closest Location: University of Chicago Medical Center · Chicago, IL
Photo of University of Chicago Medical Center 1Photo of University of Chicago Medical Center 2Photo of University of Chicago Medical Center 3
2003First Recorded Clinical Trial
3 TrialsResearching Kidney Stones
256 CompletedClinical Trials

Who is running the clinical trial?

University of ChicagoLead Sponsor
909 Previous Clinical Trials
726,923 Total Patients Enrolled
4 Trials studying Kidney Stones
768 Patients Enrolled for Kidney Stones

Eligibility Criteria

Age 18+ · All Participants · 4 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have a history of at least one calcium-based kidney stone.
You have no history of kidney stone.\n
You have 24-hour urine oxalate within lab normal (<50mg/day).

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.