Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
What You Need to Know Before You Apply
What is the purpose of this trial?
The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall fibrosis (%) of the left atrial wall area. The investigators hypothesize that patients with a higher baseline Utah fibrosis staging will experience a higher incidence of POAF.The study also aims to evaluate and compare the in-hospital mortality, length-of-stay (LOS), complication rates (strokes, pneumonia, respiratory failure etc.) of the different Utah fibrosis stage cohorts. Perform cost analysis and compare between patients with POAF and patients without POAF. The investigators hypothesize that patients experiencing POAF will have a higher mortality rate, longer LOS, greater complications, and therefore, additional hospital costs.
Who Is on the Research Team?
Nassir Marrouche, MD
Principal Investigator
Tulane University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-surgery Assessment
Baseline MRI is performed to assess atrial fibrosis and assign Utah stages
Surgery and Immediate Post-operative Monitoring
Patients undergo cardiac surgery and are monitored for atrial arrhythmias using telemetry and ECG
Follow-up
Participants are monitored for safety and effectiveness after treatment, including incidence of complications and hospital costs
What Are the Treatments Tested in This Trial?
Interventions
- Cardiac Surgery
Find a Clinic Near You
Who Is Running the Clinical Trial?
Tulane University
Lead Sponsor