Heparin for Radial Artery Occlusion

(EASY-Heparin Trial)

Overseen By Michele Jadin

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Olivier F. Bertrand

Disqualifiers: Informed consent, Local condition, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 day

500 Participants Needed

Trial Summary

What is the purpose of this trial?

Randomized study comparing the systematic use of heparin (standard of care) against an elective use of heparin to prevent radial artery occlusion after a percutaneous catheterization using a dual-artery compression system.

Eligibility Criteria

This trial is for individuals who have undergone percutaneous catheterization and are at risk of radial artery occlusion. Specific eligibility criteria details were not provided, so it's unclear who exactly can or cannot participate.

Inclusion Criteria

I am referred for a diagnostic procedure through the wrist artery.

Exclusion Criteria

Presence of plethysmographic waveform with simultaneous radial and ulnar occlusive compression (due to collaterals or interosseous artery) precluding the evaluation of patent hemostasis

I have a condition that prevents access through my wrist for procedures.

I am unable to understand the study details or give informed consent.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo a diagnostic trans-radial catheterization with either systematic or selective use of heparin

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including evaluation of complications

30 days

Treatment Details

Interventions

• Heparin
• No heparin

Trial Overview The study is examining if using heparin routinely (as standard care) is more effective than using it selectively to prevent blockage in the radial artery after a catheter procedure with dual-artery compression.

Participant Groups

Group I: No heparin Experimental Treatment 1 Intervention

No heparin administered after diagnostic only trans-radial catheterization and a dual-artery compression device for hemostasis.

Group II: Heparin Active Control 1 Intervention

Standard of care with 70-100 IU/kg of heparin after a diagnostic only trans-radial catheterization and a dual-artery compression device for hemostasis.

Who Is Running the Clinical Trial?

Olivier F. Bertrand

Lead Sponsor

Trials

3

Recruited

600+