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Sentence Training for Aphasia

N/A
Recruiting
Led By Jiyeon Lee, PhD
Research Sponsored by Purdue University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Normal or corrected to normal hearing and vision
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from baseline up to 1-week post training or 2-month post treatment
Awards & highlights

Study Summary

This trial is testing a new way to help people with aphasia, a condition that affects language skills. Researchers will study how best to prime patients for maximal learning, then use that information to develop a new treatment.

Who is the study for?
This trial is for English-speaking adults who had a stroke in the left hemisphere of their brain at least 6 months ago, causing aphasia. They should have completed high school and have normal or corrected vision and hearing. Participants must struggle with forming sentences but can use some words independently. Those with uncontrolled mental health issues, substance abuse, severe speech apraxia, or other neurological conditions affecting communication cannot join.Check my eligibility
What is being tested?
The study is testing a new method to improve sentence formation and understanding in people with aphasia using 'implicit priming'. Researchers will first identify the most effective priming conditions for learning enhancement before developing and evaluating a novel treatment based on these initial findings.See study design
What are the potential side effects?
Since this intervention involves language training exercises rather than medication or invasive procedures, traditional physical side effects are not expected. However, participants may experience fatigue or frustration during the learning process.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
My hearing and vision are normal, or corrected to be normal.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from baseline up to 1-week post training or 2-month post treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and from baseline up to 1-week post training or 2-month post treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Comprehension of target sentences in a sentence-to-picture matching task
Production of target sentences on action description pictures
Real-time comprehension of target sentences in a sentence-to-picture matching task
Secondary outcome measures
Connected speech production - picture description
Connected speech production - story retell
Production of untrained sentences on action describing pictures

Trial Design

1Treatment groups
Experimental Treatment
Group I: Structural priming trainingExperimental Treatment1 Intervention
Participants will be enrolled in 3 sessions of structural priming training (for experiment 1-3) or up to 15 treatment sessions (for experiment 4). Each session will be about 2 hour long, consisting of a set of tasks, including repeating, making, and remembering various types of sentences. In experiment 1-3, each participant will receive two different experimental priming conditions that are being compared within each session. In experiment 4, participants will receive a structural priming treatment in a single-subject design.

Find a Location

Who is running the clinical trial?

Purdue UniversityLead Sponsor
224 Previous Clinical Trials
72,660 Total Patients Enrolled
Temple UniversityOTHER
297 Previous Clinical Trials
82,869 Total Patients Enrolled
3 Trials studying Aphasia
448 Patients Enrolled for Aphasia
University of California, San DiegoOTHER
1,121 Previous Clinical Trials
1,520,820 Total Patients Enrolled

Media Library

Sentence Production Training Clinical Trial Eligibility Overview. Trial Name: NCT05415501 — N/A
Aphasia Research Study Groups: Structural priming training
Aphasia Clinical Trial 2023: Sentence Production Training Highlights & Side Effects. Trial Name: NCT05415501 — N/A
Sentence Production Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT05415501 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the aggregate amount of participants engaged in this clinical trial?

"Affirmative. The clinical trial's page on clinicaltrials.gov states that it is actively recruiting, having been initially posted on August 1st 2021 and last edited on June 10th 2022. A total of 104 patients are being sought from a single medical centre."

Answered by AI

Is participation in this trial open to me at this time?

"This clinical trial is recruiting 104 individuals between 21 and 85 years old who suffer from post-stroke aphasia. The prerequisites for entry include: verbal communication limitation, 6 months of recovery since the left hemisphere stroke event, native English speakers with corrected normal vision/hearing acuity, high school diploma or equivalent, as well as an aptitude to use words independently."

Answered by AI

Is enrollment for this research endeavor currently being accepted?

"Affirmative. Information available on clinicaltrials.gov indicates that this medical experiment is presently recruiting volunteers, having first been posted on August 1st 2021 and most recently updated June 10th 2022. The research requires 104 subjects to be sourced from a single site."

Answered by AI

Is the age restriction for this trial allowing individuals who are 45 and older?

"This trial's criteria calls for participants to be between 21 and 85 years of age."

Answered by AI

Who else is applying?

How old are they?
18 - 65
What site did they apply to?
Purdue University
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Sentence Production Training in Aphasia
Ji Yeon Lee 2021. "Sentence Production Training in Aphasia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05415501.
All > Aphasia
~46 spots leftby May 2026
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