Essential Oil Inhalation for Stress
(DMA Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This randomized, double-blind, placebo-controlled study evaluates the acute physiological and subjective responses to essential oil inhalation in healthy adults. Participants are assigned to inhale either an essential oil or a placebo via an aroma stick during standardized laboratory procedures designed to induce temporary psychosocial stress (Trier Social Stress Test - Group version) and during a guided relaxation session.
Physiological responses, including heart rate, heart rate variability, and electrodermal activity, are measured using a wearable sensor. Subjective stress and affect are assessed using validated questionnaires and visual analog scales. The purpose of this study is to characterize short-term autonomic and self-reported responses associated with essential oil inhalation under controlled experimental conditions. This study is exploratory and is not intended to diagnose, treat, or prevent any medical condition.
Who Is on the Research Team?
Nicole Stevens, PhD
Principal Investigator
DoTERRA International LLC.
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo essential oil or placebo inhalation during stress induction and guided relaxation procedures
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Essential Oil Inhalation
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Participants inhale an essential oil or essential oil blend via an individual aroma stick during standardized stress induction (TSST-G) and guided relaxation procedures across two study visits.
Participants inhale a placebo aroma stick matched in appearance and delivery method but without active essential oil components during identical stress and relaxation procedures.
Find a Clinic Near You
Who Is Running the Clinical Trial?
dōTERRA International
Lead Sponsor
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