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Improved Sleep Habits for Adolescent Depression (MoDA Trial)

N/A

Recruiting

Led By Melynda D Casement, PhD

Research Sponsored by University of Oregon

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 months

Awards & highlights

MoDA Trial Summary

This trial will explore how sleeping habits, stress, and depression are connected in teens, to develop better prevention strategies.

Who is the study for?

Adolescents aged 14-19, currently in high school with fluent English skills. They must have experienced significant stress (score >4 on STRAIN) and exhibit certain sleep patterns: either short/late or long/early as per the Munich Chronotype Questionnaire. Participants should also show depressive symptoms but not have severe psychiatric disorders, substance abuse issues, or conditions that conflict with study procedures.Check my eligibility

What is being tested?

The trial is exploring how changing sleep patterns can affect depression and lack of pleasure (anhedonia) in teenagers. It involves adjusting their sleep to be longer and earlier or maintaining regular sleep duration/timing while examining brain function related to stress and reward.See study design

What are the potential side effects?

Since this trial involves non-medical interventions like modifying sleep schedules, side effects are minimal but may include temporary changes in mood or alertness due to altered sleeping patterns.

MoDA Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Dimensional Anhedonia Rating Scale (DARS)

Patient-Reported Outcomes Measurement Information System (PROMIS) Pediatric Depression Scale - Short Form (8-item)

Patient-Reported Outcomes Measurement Information System (PROMIS) Pediatric Positive Affect Scale - Short Form (8-item)

+2 more

MoDA Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Sleep extension and advance "Lark Routine"Experimental Treatment1 Intervention

Participants go to bed 90 minutes earlier than their typical average bedtime to extend sleep duration and advance sleep timing

Group II: Regular sleep duration and timing "Owl Routine"Active Control1 Intervention

Participants go to bed at their typical average bedtime

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of OregonLead Sponsor

80 Previous Clinical Trials

46,756 Total Patients Enrolled

11 Trials studying Depression

3,692 Patients Enrolled for Depression

Oregon Research InstituteOTHER

84 Previous Clinical Trials

66,117 Total Patients Enrolled

10 Trials studying Depression

2,442 Patients Enrolled for Depression

University of PittsburghOTHER

1,722 Previous Clinical Trials

16,342,796 Total Patients Enrolled

119 Trials studying Depression

33,945 Patients Enrolled for Depression

Media Library

Sleep extension and advance "Lark Routine" Clinical Trial Eligibility Overview. Trial Name: NCT05691439 — N/A

Depression Research Study Groups: Sleep extension and advance "Lark Routine", Regular sleep duration and timing "Owl Routine"

Depression Clinical Trial 2023: Sleep extension and advance "Lark Routine" Highlights & Side Effects. Trial Name: NCT05691439 — N/A

Sleep extension and advance "Lark Routine" 2023 Treatment Timeline for Medical Study. Trial Name: NCT05691439 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is eligibility limited to those under sixty or can seniors also partake in this experiment?

"The age requirements for this investigation mandates that participants be at least 14 years old, but not older than 19."

Answered by AI

How many participants are there in the current research endeavor?

"Yes, the information on clinicaltrials.gov indicates that recruitment for this trial is currently ongoing. This study was first posted on March 27th 2023 and has since been modified as of April 11th 2023. At present, 150 participants are needed at a single site to complete enrollment goals."

Answered by AI

Are any additional participants currently being sought for this research study?

"Indeed, the info on clinicaltrials.gov asserts that this medical trial is still open for recruitment. It was first uploaded in March 27th 2023 and its details have since been revised as of April 11th 2023. The study requires 150 patients from a single location to be enrolled."

Answered by AI

Does my profile match the criteria necessary to participate in this research?

"The trial is looking for 150 adolescents aged 14 to 19, who are currently attending high school and report either short-late or long-early sleep patterns. Additionally, participants must have experienced more than four lifetime stressful events as measured by the STRAIN scale and show a depressive severity of 45 T-score on PROMIS' Depression scale."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

Melynda Casement 2023. "Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05691439.