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Extra Virgin Olive Oil for Alzheimer's Disease Risk

N/A
Waitlist Available
Research Sponsored by Auburn University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 months
Awards & highlights

Study Summary

This trial will explore whether taking extra-virgin olive oil has an effect on genes, metabolites, and lipids for people with a family history of Alzheimer's.

Who is the study for?
This trial is for healthy individuals with a family history of Alzheimer's Disease. Participants should be cognitively normal and not have any neuropsychiatric illnesses like depression or anxiety. Smokers and pregnant women, or those who become pregnant during the study, are excluded.Check my eligibility
What is being tested?
The study tests if consuming extra virgin olive oil (EVOO) daily (~2 tablespoons) can induce beneficial gene and metabolic changes in healthy subjects at risk for Alzheimer's due to family history. Blood samples will be analyzed before and after six months of EVOO intake.See study design
What are the potential side effects?
Extra virgin olive oil is generally considered safe; however, high doses may lead to digestive issues such as diarrhea. It might also cause allergic reactions in very rare cases.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Changes in the concentrations of blood mRNA transcripts (transcriptomics)
Changes in the concentrations of blood metabolites (metabolomics)

Trial Design

2Treatment groups
Active Control
Group I: ControlActive Control1 Intervention
This group will not receive intervention
Group II: Extra-virgin olive oilActive Control1 Intervention
This group will receive extra-virgin olive oil (EVOO) as intervention

Find a Location

Who is running the clinical trial?

Auburn UniversityLead Sponsor
72 Previous Clinical Trials
14,365 Total Patients Enrolled

Media Library

Alzheimer's Disease Research Study Groups: Control, Extra-virgin olive oil

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are subjects aged 20 or older being accepted into this research project?

"According to the official requirements for this trial, only individuals between 35 and 55 years of age may be eligible."

Answered by AI

Are there any openings to join this clinical trial at the present time?

"Per clinicaltrials.gov, this experiment is no longer enlisting patients - the post was published on 8/1/2023 and last modified 7/1/2023. Although recruitment for this study has closed, there are 524 other trials actively recruiting participants at present."

Answered by AI

Is participation in this clinical experiment attainable?

"Candidates aged 35-55 with Alzheimer's disease are encouraged to apply for this trial, of which 40 subjects will be recruited."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Does EVOO Induce Gene and Metabolic Changes in Healthy Subjects
Amal Kaddoumi 2023. "Does EVOO Induce Gene and Metabolic Changes in Healthy Subjects". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05929924.
~12 spots leftby Sep 2024
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