Flavanol Intake Study for Adults
(FID Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand flavanol consumption (a compound found in foods like apples and tea) by analyzing participants' urine. Researchers will examine flavanol breakdown products to learn about dietary intake patterns. The trial seeks adults in Davis and the greater Sacramento area who can communicate via video calls and have a BMI between 18.5 and 34.9.
As an unphased trial, this study offers participants the chance to contribute to important nutritional research that could enhance understanding of dietary habits and health.
What prior data suggests that this method is safe?
Research has shown that flavanols, found in foods like apples, berries, and tea, are generally safe for people. Studies have found that these compounds can be consumed as part of a regular diet without major problems. The body breaks down flavanols into smaller parts called metabolites, which it handles well.
In past research, participants who consumed flavanols did not report serious side effects, suggesting that flavanols are well-tolerated. However, like any food, it's important to consume them in moderation. Overall, existing evidence supports the safety of flavanols when eaten in typical amounts.
Why are researchers excited about this trial?
Researchers are excited about estimating flavanol intake using biomarkers because it offers a new way to understand how these compounds affect health. Unlike current nutritional assessments that often rely on self-reported dietary data, this method uses biological markers to provide more accurate and objective information. This approach could lead to better insights into how flavanols contribute to health benefits, potentially influencing dietary guidelines and interventions. By refining our understanding of nutrient intake, this method paves the way for more personalized and effective nutritional recommendations.
What evidence suggests that this study's methods could be effective for understanding flavanol consumption?
Research has shown that flavanols, found in foods like apples, berries, and tea, can benefit health. Some studies suggest they might support heart health by lowering blood pressure. Flavanols may also improve blood flow and protect cells due to their antioxidant effects. However, most findings come from general health studies rather than those focused on specific conditions. While flavanols appear promising, more research is needed to confirm their effectiveness for particular health issues.
Who Is on the Research Team?
Francene M. Steinberg, PhD, RD
Principal Investigator
University of California, Davis
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Initial assessment of biomarker-estimated (-)-epicatechin and flavanol intake through urine samples and other health metrics
Data Collection
Collection of urine samples to assess biomarker-estimated flavanol intake and other health metrics
Follow-up
Participants are monitored for any changes in biomarker-estimated flavanol intake and health metrics
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Davis
Lead Sponsor
Mars, Inc.
Industry Sponsor