Study Summary
This trial will study the effects of different interventions on HIV viral suppression among 840 adolescents living with HIV. The investigators will test the effects of a group-based HIV stigma reduction intervention for educators, multiple family groups with HIV stigma reduction combined with family economic empowerment, or Bolstered Standard of Care.
Eligible Conditions
- HIV/AIDS
Treatment Effectiveness
Effectiveness Progress
Study Objectives
1 Primary · 3 Secondary · Reporting Duration: Baseline 12, 24 and 36 month follow-up
Month 36
Beck Hopelessness Scale (BHS)
Caregiver mental health
Change HIV viral suppression
Change in Adherence and retention in care
Child Depression Inventory (CDI)
Family relations
Financial Literacy
HIV Adherence Self-Efficacy Scale
HIV Stigma Measure for Children
Post-Traumatic Stress Disorder (PTSD)
Rosenberg Self-Esteem Scale
Savings Deposits
Social Support Behaviors Scale
Tennessee Self-Concept Scale (TSCS)
The Shame Questionnaire for Children
Trial Safety
Safety Progress
Trial Design
2 Treatment Groups
Treatment Arm 1
1 of 2
Treatment Arm 2
1 of 2
Experimental Treatment
840 Total Participants · 2 Treatment Groups
Primary Treatment: Bolstered Standard of Care (BSOC) · No Placebo Group · N/A
Treatment Arm 1Experimental Group · 2 Interventions: Bolstered Standard of Care (BSOC), Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE · Intervention Types: Other, Behavioral
Treatment Arm 2Experimental Group · 3 Interventions: Bolstered Standard of Care (BSOC), Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE plus Group-based stigma reduction for educators (GED-HIVSR)., Multiple Family Groups for HIV stigma reduction (MFG-HIVSR) plus FEE · Intervention Types: Other, Behavioral, Behavioral
Trial Logistics
Trial Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline 12, 24 and 36 month follow-up
Who is running the clinical trial?
National Institute of Mental Health (NIMH)NIH
2,560 Previous Clinical Trials
1,823,001 Total Patients Enrolled
Washington University School of MedicineLead Sponsor
1,805 Previous Clinical Trials
2,277,775 Total Patients Enrolled
Eligibility Criteria
Age 10 - 17 · All Participants · 5 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:References
- Mutumba M, Ssewamala F, Namirembe R, Sensoy Bahar O, Nabunya P, Neilands T, Tozan Y, Namuwonge F, Nattabi J, Acayo Laker P, Mukasa B, Mwebembezi A. A Multilevel Integrated Intervention to Reduce the Impact of HIV Stigma on HIV Treatment Outcomes Among Adolescents Living With HIV in Uganda: Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2022 Oct 5;11(10):e40101. doi: 10.2196/40101.
- Fred Ssewamala 2022. "M-Suubi: A Multi-Level Integrated Intervention to Reduce the Impact of HIV Stigma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05307250.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Conditions
Cancer Related
Treatments