Telerehabilitation for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new telerehabilitation program for individuals with lymphoma or myeloma scheduled to receive CAR-T therapy. The program, called Multimodal Telerehabilitation, combines personalized exercise, nutrition plans, and interactive education, all managed online from home. The researchers aim to determine if this approach can improve quality of life and better manage symptoms. Participants must have a confirmed diagnosis of lymphoma or myeloma and plan to receive CAR-T therapy in at least four weeks. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance patient care and quality of life.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that this telerehabilitation model is safe for cancer patients?
Research has shown that telerehabilitation is generally safe for cancer patients. In a study with 123 cancer survivors, this method proved safe and improved health. Patients adhered well to the program and reported positive experiences. These findings suggest that the treatment is safe for home use, enabling patients to follow personalized exercise and nutrition plans with ongoing support.12345
Why are researchers excited about this trial?
Researchers are excited about the multimodal telerehabilitation approach for cancer patients because it offers a personalized and interactive method for managing and improving health during and after CAR-T therapy. Unlike traditional rehabilitation, which often requires in-person visits, this approach uses an app and web-based portal to provide exercise, nutrition plans, and educational support right at home. By combining technology with behavioral counseling and social support, it empowers patients to actively participate in their recovery, potentially leading to better outcomes and quality of life.
What evidence suggests that this multimodal telerehabilitation is effective for cancer?
Research shows that telerehabilitation can help cancer patients. Studies have found that cancer survivors using telerehabilitation experience better health and less pain. This method allows patients to exercise at their own pace from home and offers support through interactive technology, enhancing their quality of life. In this trial, participants will undergo a four-week multimodal prehabilitation before CAR-T therapy, followed by a 12-week home-based multimodal telerehabilitation. Early results suggest that patients receiving CAR-T therapy find telerehabilitation easy to use and adhere to. Overall, telerehabilitation is a promising way to aid cancer recovery.12456
Who Is on the Research Team?
Douglas Sborov, MD, MS
Principal Investigator
Huntsman Cancer Institute/ University of Utah
Are You a Good Fit for This Trial?
This trial is for adults over 21 with lymphoma or myeloma who are scheduled to receive FDA-approved CAR-T therapy in at least 4 weeks. They should be able to perform daily activities with varying degrees of assistance (ECOG status 0-2) and have access to a phone.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Prehabilitation
Participants undergo a four-week multimodal prehabilitation before the commencement of the CAR-T therapy, including resistance, aerobic, and relaxation exercises, and a nutrition plan.
CAR-T Therapy and Chemotherapy
Participants receive chemotherapy, CAR-T infusion, and undergo in-hospital toxicity monitoring and recovery. Continuous online empowerment and education support are provided during this phase.
Telerehabilitation
After hospital discharge, participants undergo a 12-week home-based multimodal telerehabilitation program, including exercise, nutrition, and social support via group telecounseling sessions.
Follow-up
Participants are monitored for safety and effectiveness after treatment, with assessments of QoL, fitness, and patient-reported outcomes.
What Are the Treatments Tested in This Trial?
Interventions
- Multimodal Telerehabilitation
Trial Overview
The study tests a home-based telerehabilitation system that helps patients follow personalized exercise and nutrition plans, supported by technology for safety monitoring and interactive education. It aims to improve quality of life, function, and manage symptoms remotely.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Each enrolled patient will undergo a four-week multimodal prehabilitation before the commencement of the CAR-T therapy. During CAR-T therapy, the patients will use an interactive app supporting cancer self-care education and early mobilization while undergoing chemotherapy, infusion, in-hospital toxicity monitoring, and recovery (the duration depends on the specific CAR-T treatment regimen). After completion of the CAR-T procedures and hospital discharge, the patients will undergo a 12-week home-based multimodal telerehabilitation. Individualized rehabilitation plans using a web-based care management portal. Patients at home follow a safe and effective personalized exercise and nutrition plan guided by interactive touch-screen technology combined with behavioral counseling, social support, and interactive education and empowerment.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Utah
Lead Sponsor
United States Department of Defense
Collaborator
Citations
Multimodal Telerehabilitation in Patients Undergoing CAR ...
This study will determine if patients with hematologic malignancies undergoing CAR-T therapy will demonstrate sufficient acceptability and adherence to the ...
2.
ctv.veeva.com
ctv.veeva.com/study/multimodal-telerehabilitation-in-patients-undergoing-car-t-cell-immunotherapyMultimodal Telerehabilitation in Patients Undergoing CAR-T Cell ...
This study will determine if patients with hematologic malignancies undergoing CAR-T therapy will demonstrate sufficient acceptability and adherence to the ...
The influence of telehealth-based cancer rehabilitation ... - PMC
The most commonly reported outcome measures were the Functional Assessment of Cancer Therapy—General (n = 13, 19%), Medical Outcomes Study ...
4.
journals.lww.com
journals.lww.com/md-journal/fulltext/2025/02210/feasibility_and_effects_of_the_telerehabilitation.29.aspxFeasibility and effects of the telerehabilitation program...
Telerehabilitation allows cancer survivors to exercise conveniently and at their own pace, improving outcomes, and reducing pain and hospital ...
Relaxation training via tele-rehabilitation program in ...
The aim of this research was to investigate the effects of relaxation exercises delivered via tele-rehabilitation in breast cancer patients ...
Feasibility and effects of the telerehabilitation program during ...
Another recent quantitative and qualitative study on 123 cancer survivors has also described that telerehabilitation is safe and feasible and improves outcomes.
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