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Strength Training for Aging

N/A

Recruiting

Research Sponsored by Marquette University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Men and women aged 18-40 years

Men and women aged >65 years

Timeline

Screening 3 weeks

Treatment Varies

Follow Up before and 2-days after completion of resistance training intervention of 8 weeks.

Awards & highlights

Study Summary

This trial will look at how different age groups handle fatigue during exercise, and whether a specific type of training can help older adults improve their muscle power output and handle fatigue better.

Who is the study for?

This trial is for men and women aged 18-40 or over 65, without severe health issues like uncontrolled high blood pressure, diabetes, recent cancer treatment, extreme obesity (BMI ≥40), or conditions limiting exercise. Pregnant women and those on certain muscle-affecting drugs can't join.Check my eligibility

What is being tested?

The study tests how aging affects muscle tiredness during dynamic exercises and if strength training with blood flow restriction improves muscle power in older adults. It compares younger individuals to seniors using advanced techniques to measure muscle and vascular function.See study design

What are the potential side effects?

While the trial involves physical exercise which generally has benefits such as improved fitness, potential side effects may include typical exercise-related risks like muscle soreness or strain especially in older participants.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 40 years old.

Select...

I am older than 65 years.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ before and 2-days after completion of resistance training intervention of 8 weeks.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~before and 2-days after completion of resistance training intervention of 8 weeks.

This trial's timeline: 3 weeks for screening, Varies for treatment, and before and 2-days after completion of resistance training intervention of 8 weeks. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Fatigability of the knee extensor muscles from baseline to after 8 weeks training

Change in Oxygenation of the muscle between baseline to after 8 weeks of training

Change in arteriole Vasodilation from baseline to after 8 weeks of training

+5 more

Secondary outcome measures

Strength

Trial Design

2Treatment groups

Experimental Treatment

Group I: Resistance Training OnlyExperimental Treatment1 Intervention

This leg will then perform low-load resistance training (30% of 1-RM) including 3 sets of 15 knee extensions performed as fast as possible while seated upright in a knee extension weight machine. Sets will be interspersed with 30 seconds rest. This leg will always perform the training without blood flow restriction.

Group II: Blood Flow Restriction TrainingExperimental Treatment1 Intervention

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Medical College of WisconsinOTHER

610 Previous Clinical Trials

1,162,593 Total Patients Enrolled

3 Trials studying Aging

354 Patients Enrolled for Aging

Marquette UniversityLead Sponsor

62 Previous Clinical Trials

200,203 Total Patients Enrolled

2 Trials studying Aging

490 Patients Enrolled for Aging

National Institute on Aging (NIA)NIH

1,675 Previous Clinical Trials

28,020,765 Total Patients Enrolled

160 Trials studying Aging

75,887 Patients Enrolled for Aging

Media Library

Exercise Clinical Trial Eligibility Overview. Trial Name: NCT03888040 — N/A

Aging Research Study Groups: Resistance Training Only, Blood Flow Restriction Training

Aging Clinical Trial 2023: Exercise Highlights & Side Effects. Trial Name: NCT03888040 — N/A

Exercise 2023 Treatment Timeline for Medical Study. Trial Name: NCT03888040 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the age cutoff for this trial inclusive of those over 35 years old?

"As specified in the trial's requirements for inclusion, any individual aged 18 and upwards is eligible to participate, up until they reach 100 years of age."

Answered by AI

What criteria must individuals satisfy to be eligible for this experiment?

"This clinical trial seeks 120 participants of diverse age ranges, from 18 to 100 years old. More specifically, it is looking for male and female patients between the ages of 18-40 or over 65."

Answered by AI

Is the research team actively searching for candidates to participate in this experiment?

"Affirmative. According to clinicaltrials.gov, this examination is actively soliciting participants at the moment. It was first listed on September 1st 2020 and most recently edited on April 13th 2021. All in all, 120 individuals are required for enrolment across one site."

Answered by AI

How many subjects are partaking in this experiment?

"Affirmative. According to clinicaltrials.gov, the trial is actively recruiting participants since its posting on September 1st 2020 and last update on April 13th 2021. The study needs a total of 120 patients from one location for completion."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women

Sandra Hunter 2020. "Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03888040.