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Psychological Stress Impact on Navigation in Aging

N/A
Recruiting
Led By Thackery I Brown, Ph.D.
Research Sponsored by Georgia Institute of Technology
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 1.5 years
Awards & highlights

Study Summary

This trial will study how stress affects aging adults' ability to navigate and remember locations, and whether this affects their ability to plan efficient routes.

Who is the study for?
This trial is for U.S. citizens or permanent residents aged 65-80 who speak fluent English and can visit Georgia Tech for group sessions. It's not for those with metal/electrical implants, heart issues, certain medications like beta-blockers, epilepsy, dementia, Parkinson's disease, history of stroke/seizure, psychiatric disorders including untreated depression or emotional conditions, ADD/ADHD, MS, uncontrolled blood pressure issues, untreated diabetes or sickle cell anemia.Check my eligibility
What is being tested?
The study examines how stress affects memory and navigation in aging adults by assigning them to a stressed group or control group during a novel navigation task. Using neuroimaging and behavioral measures under stress-induced conditions versus normal circumstances will reveal the impact on spatial memory and route planning abilities.See study design
What are the potential side effects?
Since this trial involves psychological stress manipulation rather than medication or invasive procedures; side effects may include temporary increased anxiety or stress levels during tasks but no physical side effects are expected from the interventions themselves.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 1.5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 1.5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Behavioral probability of taking a shortcut between control and treatment groups
Neural memory representation reactivation between control and treatment groups
fMRI activation level between control and treatment groups
Secondary outcome measures
2. Salivary cortisol (stress hormone) response difference between stress and control participant groups.
Relationship between fMRI activity level and behavioral probability of taking a shortcut.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Stress groupExperimental Treatment1 Intervention
Participants in this group will perform the psychology tasks (virtual navigation) under manipulated psychological stress (anticipatory threat of shock)
Group II: No-stress control groupActive Control1 Intervention
Participants in this group will perform the psychology tasks (virtual navigation) without any manipulation of psychological stress

Find a Location

Who is running the clinical trial?

Georgia Institute of TechnologyLead Sponsor
48 Previous Clinical Trials
5,449 Total Patients Enrolled
4 Trials studying Aging
179 Patients Enrolled for Aging
National Institute on Aging (NIA)NIH
1,671 Previous Clinical Trials
28,016,978 Total Patients Enrolled
160 Trials studying Aging
75,922 Patients Enrolled for Aging
Thackery I Brown, Ph.D.Principal InvestigatorGeorgia Institute of Technology

Media Library

Anticipatory psychological stress Clinical Trial Eligibility Overview. Trial Name: NCT03896529 — N/A
Aging Research Study Groups: No-stress control group, Stress group
Aging Clinical Trial 2023: Anticipatory psychological stress Highlights & Side Effects. Trial Name: NCT03896529 — N/A
Anticipatory psychological stress 2023 Treatment Timeline for Medical Study. Trial Name: NCT03896529 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants currently being accepted for this research endeavor?

"Per the information on clinicaltrials.gov, this medical study is currently recruiting participants. It was originally posted to the database on September 24th 2019 and was recently edited on March 28th 2022."

Answered by AI

How many individuals are participating in the experimental research?

"Affirmative. The most recent update on clinicaltrials.gov, dated March 28th 2022, states that this medical trial is actively enrolling 85 patients at a single site since its inception on September 24th 2019."

Answered by AI

What eligibility criteria must prospective participants meet to take part in this trial?

"To be accepted into this trial, applicants must lie within the boundaries of 65 to 80 years old. Currently, 85 participants are being sought out for the study."

Answered by AI

Are there age restrictions for enrollment in this clinical experiment?

"For this particular research, volunteers must be between 65 and 80 years old. There are 78 trials targeting minors and 533 clinical studies focused on people of senior age."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
How old are they?
65+
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Neurobiological Mechanisms of Aging and Stress on Prospective Navigation
2019. "Neurobiological Mechanisms of Aging and Stress on Prospective Navigation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03896529.
~15 spots leftby Apr 2025
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