MRI-Guided Radiotherapy for Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a new machine that combines an MRI scan with radiotherapy can safely and clearly display cancer. The goal is to help doctors target cancer more precisely during treatment. The trial includes a single MRI session to test the image quality of this new technology, specifically using the Alberta linac-MR P3 system. It seeks adults who are prepared for high-dose radiation therapy and can remain still during the scan. As an unphased trial, this study offers a unique opportunity to contribute to the development of cutting-edge technology that could enhance the precision of cancer treatment.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that the Alberta linac-MR P3 system is safe for MR imaging?
Research has shown that the Alberta linac-MR P3 system has received approval from the Canadian Nuclear Safety Commission, confirming it meets safety standards. Previous studies have focused on ensuring that MRI-guided radiotherapy functions correctly and safely. These studies continue to ensure the machine can capture clear images without causing harm.
In another study, researchers tested the safety of MRI-guided radiotherapy, and the treatment was generally well-tolerated. No major safety concerns emerged for the MR scan itself. Overall, current evidence suggests that using the Alberta linac-MR P3 system for imaging is considered safe.12345Why are researchers excited about this trial?
The MRI-Guided Radiotherapy using the Alberta linac-MR P3 system is unique because it combines real-time MR imaging with radiation therapy to precisely target cancer cells. Unlike conventional radiotherapy, which relies on CT scans for guidance, this method allows for continuous imaging during treatment, potentially increasing accuracy and sparing healthy tissue. Researchers are excited about this approach because it could lead to more effective treatments with fewer side effects, improving patient outcomes.
What evidence suggests that the Alberta linac-MR P3 system is effective for cancer imaging?
Research has shown that MRI might detect cancers more effectively than CT scans. In this trial, all participants will undergo MR imaging on the Alberta linac-MR P3 system, which uses MRI to guide radiation therapy. This system could improve the accuracy of tumor targeting during treatment. Early results suggest that it can safely produce high-quality MRI images, enabling doctors to view tumors more clearly. This clarity could lead to more precise treatments, potentially improving outcomes such as tumor control and survival rates. This technology holds promise for transforming radiation therapy for cancer patients.24678
Who Is on the Research Team?
Nawaid Usmani, MD
Principal Investigator
Cross Cancer Institute, Alberta Health Services
Are You a Good Fit for This Trial?
This trial is for adults over 18 who are fit for high dose radiation therapy as determined by their oncologist. It's not suitable for those unable to lie flat and still during scans, cannot consent, or have conditions that make MRI use unsafe.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
MR Imaging
Participants undergo a single MR imaging session on the Alberta linac-MR P3 system
Optional Sub-study
Participants may undergo additional MR imaging sessions to assess inter-fraction motion
Follow-up
Participants are monitored for safety and effectiveness after imaging sessions
What Are the Treatments Tested in This Trial?
Interventions
- MR scan with the Alberta linac-MR P3 system
Find a Clinic Near You
Who Is Running the Clinical Trial?
AHS Cancer Control Alberta
Lead Sponsor