MRI-Guided Radiotherapy for Cancer
Trial Summary
What is the purpose of this trial?
Cancers are often treated with external beam radiotherapy. Current radiotherapy treatments are performed using computed tomography (also known as CT) scans which may not always clearly identify the cancer. In some instances, magnetic resonance imaging (MRI) may be able to better identify cancers. Therefore, efforts are currently underway to use the MRI scans to improve radiotherapy treatments or eventually even use radiotherapy equipment that only uses MRI scans to guide treatments. This new technology that will only use MRI scans to guide treatments is called the Linac-MR (linear accelerator with an MRI). The purpose of this pilot phase of the study is to test whether the Alberta linac-MR P3 system at the Cross Cancer Institute can acquire high quality MR images safely. It will allow the researchers to develop the best collection of MR images possible with this new machine, in order to allow them to visualize tumors for future patients that are treated on this machine.
Research Team
Nawaid Usmani, MD
Principal Investigator
Cross Cancer Institute, Alberta Health Services
Eligibility Criteria
This trial is for adults over 18 who are fit for high dose radiation therapy as determined by their oncologist. It's not suitable for those unable to lie flat and still during scans, cannot consent, or have conditions that make MRI use unsafe.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
MR Imaging
Participants undergo a single MR imaging session on the Alberta linac-MR P3 system
Optional Sub-study
Participants may undergo additional MR imaging sessions to assess inter-fraction motion
Follow-up
Participants are monitored for safety and effectiveness after imaging sessions
Treatment Details
Interventions
- MR scan with the Alberta linac-MR P3 system
Find a Clinic Near You
Who Is Running the Clinical Trial?
AHS Cancer Control Alberta
Lead Sponsor