Goal-Management Training for HIV
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how goal management training might help people with HIV improve brain health and overall well-being. It examines whether setting personal goals before starting a healthy lifestyle program can enhance memory, concentration, and problem-solving skills. Participants will receive either a combination of goal management training with a healthy lifestyle program or just the healthy lifestyle program alone. Individuals who have lived with HIV for at least a year and experience challenges like forgetfulness or trouble focusing might be a good fit for this study. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance the quality of life for those living with HIV.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that goal-management training is safe for individuals with HIV?
Research has shown that Goal-Management Training (GMT) is generally safe and easy to handle. In studies, people with stable HIV have used GMT and found it manageable and acceptable, meaning they could do it without much difficulty. The studies reported no serious side effects or safety issues. This suggests that GMT is a low-risk option for those considering joining the clinical trial.12345
Why are researchers excited about this trial?
Researchers are excited about goal-management training (GMT) for individuals with HIV because it offers a novel approach to cognitive rehabilitation. Unlike traditional treatments that primarily focus on managing physical symptoms of HIV, GMT targets cognitive functions, aiming to improve patients' mental organization and goal-setting abilities. This approach is combined with a Healthy Lifestyle Program, which uses modern technology like activity trackers and goal-monitoring apps, empowering participants to take an active role in their health management. By addressing both cognitive and physical aspects, this combined strategy may offer a more holistic improvement in quality of life for those living with HIV.
What evidence suggests that goal-management training is effective for improving brain health in individuals with HIV?
Research has shown that Goal Management Training (GMT), which participants in this trial may receive, can greatly enhance thinking skills, such as memory and focus, in people with HIV. One study found that those who used GMT noticed clear improvements in their mental abilities. Another study highlighted that GMT might assist people with HIV who face brain-related challenges. Further research suggests that GMT leads to moderate but lasting improvements in skills like planning and decision-making. Overall, these findings indicate that GMT could be a valuable tool for boosting brain health in people living with HIV.24678
Who Is on the Research Team?
Nancy Mayo, PhD
Principal Investigator
McGill University
Marie-Josée Brouillette, MD
Principal Investigator
McGill University
Lesley Fellows, PhD/MD
Principal Investigator
McGill University
Are You a Good Fit for This Trial?
This trial is for individuals who have been living with HIV for at least a year, can consent in French or English, and show signs of cognitive frailty or don't meet 'successful aging' criteria. It's not suitable for those unable to do moderate exercise, with a life expectancy under 3 years, active brain infections, hepatitis C needing treatment during the study, dementia affecting cognition, other neurological disorders impacting thinking skills, psychosis or recent substance abuse.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Ready, Set Workshop
Participants attend a workshop to learn about the My Personal Brain Health Dashboard and receive training on using the Garmin vívofit 4 Activity Tracker and the My Goals app.
Treatment
Participants are randomized to either Goal Management Training (GMT) with Healthy Lifestyle Program (HLP) or HLP alone. The GMT group undergoes 9 sessions of cognitive rehabilitation over 9 weeks.
Follow-up
Participants are monitored for adherence to health recommendations and achievement of health-related goals.
What Are the Treatments Tested in This Trial?
Interventions
- Control
- Goal-management training
Trial Overview
The trial tests if adding Goal Management Training (GMT) to a Healthy Lifestyle Program (HLP) leads to better adherence to health recommendations and outcomes than the HLP alone. Participants will be randomly assigned either GMT plus HLP or just HLP and their brain health and general health outcomes will be compared.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
The intervention group will participate in GMT, a standardized cognitive rehabilitation program which will be given as per the manual and which consists of 9 sessions each 2-hours in duration. They will also participate in the Healthy Lifestyle Program (HLP), which includes physical activity monitoring (step count, calories burned and sleep) with the Garmin vívofit 4 Activity Tracker, and recording and monitoring of goals with the My Goals app. Moreover, participants will be offered an exercise program with weaning to community-based resources and home exercise recommendations for longer-term sustainability.
The control group enters directly into the HLP without any other study visits. The HLP includes physical activity monitoring (step count, calories burned and sleep) with the Garmin vívofit 4 Activity Tracker, and recording and monitoring of goals with the My Goals app. Moreover, participants will be offered an exercise program with weaning to community-based resources and home exercise recommendations for longer-term sustainability.
Find a Clinic Near You
Who Is Running the Clinical Trial?
McGill University
Lead Sponsor
Citations
Efficacy potential of Goal Management Training to improve ...
There was a meaningful improvement in self-reported cognition in those adherent to the intervention. GMT is a promising intervention for people ...
Efficacy potential of Goal Management Training to improve ...
The aim of this study was to ascertain feasibility, acceptability, and efficacy potential of GMT for people (≥50 years) with stable HIV infection scoring low on ...
Abbreviated Goal Management Training Shows ...
This study examined the effectiveness of Goal Management Training (GMT) alone or GMT as part of a metacognitive training among HIV/SUD individuals with ...
Canadian Foundation for AIDS Research
Efficacy potential of goal management training to improve cognitive function in ... Goal Management training in people living with HIV. Sponsor.
Effectiveness of goal management training® in improving ...
The analysis suggests that GMT is an effective intervention, leading to moderate improvements in executive functions that are usually maintained at follow-up.
Efficacy potential of Goal Management Training to improve ...
The aim of this study was to ascertain feasibility, acceptability, and efficacy potential of GMT for people (≥50 years) with stable HIV ...
7.
researchgate.net
researchgate.net/publication/365072383_Efficacy_potential_of_Goal_Management_Training_to_improve_cognitive_function_in_older_people_living_with_HIVEfficacy potential of Goal Management Training to improve ...
The aim of this study was to ascertain feasibility, acceptability, and efficacy potential of GMT for people (≥50 years) with stable HIV infection scoring low on ...
8.
frontiersin.org
frontiersin.org/journals/rehabilitation-sciences/articles/10.3389/fresc.2025.1644139/fullGoals in motion: exploring goal setting among adults living ...
We conducted a multi-method, longitudinal, observational study using data from an online community-based exercise (CBE) intervention study (12).
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