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Diagnostic Test

Low-Dose PET/CT Imaging Techniques

N/A

Waitlist Available

Led By Michael V Knopp, MD, PhD

Research Sponsored by University of Cincinnati

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, on average 2-5 years

Awards & highlights

Study Summary

This trial is testing new, low-dose radiation techniques for PET/CT scans.

Who is the study for?

This trial is for adults over 18 who are scheduled for a standard PET/CT scan and can lie flat during the procedure. Women able to have children must meet specific requirements for imaging agents and CT exams. Pregnant or breastfeeding individuals, prisoners, or those unable to consent are excluded.Check my eligibility

What is being tested?

The study is testing new low-dose radiation techniques for PET/CT scans by comparing them with the current standard dose. Each participant will receive both a standard dose scan and one of several lower doses within one week.See study design

What are the potential side effects?

Since this trial involves different doses of radiation used in PET/CT scans, potential side effects may include temporary discomfort from lying still, but risks associated with exposure to low-level radiation are minimal.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, on average 2-5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, on average 2-5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, on average 2-5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Image quality

Secondary outcome measures

Artifacts

Image noise

Lesion detectability

Trial Design

6Treatment groups

Experimental Treatment

Group I: Sub-Study FExperimental Treatment2 Interventions

Patients receive PET/SCAN using system that did not show equivalence in Sub-Study A-C

Group II: Sub-Study EExperimental Treatment2 Interventions

Patients receive lower radiation dose on Vereos 128 digital PET/CT

Group III: Sub-Study DExperimental Treatment2 Interventions

Patients receive PET/CT scan on Vereos 128 digital PET/CT

Group IV: Sub-Study CExperimental Treatment2 Interventions

Patients receive PET/CT scan on Discovery PET/CT

Group V: Sub-Study BExperimental Treatment2 Interventions

Patients receive PET/CT scan on Biograph mCT

Group VI: Sub-Study AExperimental Treatment2 Interventions

Patients receive PET/CT scan on Gemini Astonish PET/CT

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of CincinnatiLead Sponsor

428 Previous Clinical Trials

634,196 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,657 Previous Clinical Trials

40,933,477 Total Patients Enrolled

Ohio Third FrontierOTHER

5 Previous Clinical Trials

501 Total Patients Enrolled

Media Library

PET/CT scan with 13 mCi radiation dose (Diagnostic Test) Clinical Trial Eligibility Overview. Trial Name: NCT03519659 — N/A

Positron Emission Tomography/Computed Tomography Imaging Research Study Groups: Sub-Study B, Sub-Study C, Sub-Study E, Sub-Study F, Sub-Study D, Sub-Study A

Positron Emission Tomography/Computed Tomography Imaging Clinical Trial 2023: PET/CT scan with 13 mCi radiation dose Highlights & Side Effects. Trial Name: NCT03519659 — N/A

PET/CT scan with 13 mCi radiation dose (Diagnostic Test) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03519659 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities to participate in this research endeavor?

"Affirmative. As per the clinicaltrials.gov website, this study is actively scouting for participants and was originally advertised on July 21st 2015 before being updated most recently on April 15th 2022. The research requires 204 volunteers to be recruited from 1 site."

Answered by AI

How many participants are being trialed for this therapeutic intervention?

"Affirmative. The data posted to clinicaltrials.gov clarifies that this research project, initially listed on July 21st 2015, is still recruiting patients for participation. In total, 204 individuals are needed from a single medical site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Validating Low FDG Dose PET/CT Compared to Current Standard of Care Dose PET/CT

Michael V Knopp MD PhD 2015. "Validating Low FDG Dose PET/CT Compared to Current Standard of Care Dose PET/CT". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03519659.