This trial is evaluating whether Aspirin 81Mg Ec Tab will improve 6 primary outcomes, 18 secondary outcomes, and 4 other outcomes in patients with Peripheral Arterial Disease. Measurement will happen over the course of Baseline to 37 days.
This trial requires 75 total participants across 2 different treatment groups
This trial involves 2 different treatments. Aspirin 81Mg Ec Tab is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 4 and have been shown to be safe and effective in humans.
"Patients without a known thromboembolic risk, with and without aortic valve disease, who develop symptomatic thrombus may be found to have atrial fibrillation and/or hypertension. Patients with a known thromboembolic risk, with or without underlying aortic valve disease, should be evaluated as patients are found to have a high (3% or greater) long-term risk of thromboembolism." - Anonymous Online Contributor
"Thrombus is a blood clot that interrupts circulation by disrupting blood flow through a blood vessel. If left untreated, thrombus may lead to heart attacks and possibly death. In the case of heart attacks, a thrombus can be surgically removed. Thrombus, and related condition thrombophlebitis, can contribute to the development of deep vein thrombosis (DVT)." - Anonymous Online Contributor
"Results from a recent paper suggests that a significant proportion of the population (29.3%) of Caucasian women and 20.4% of African American women are unlikely to get adequate antithrombotic prophylaxis. This is a matter that warrants broader study since thrombotic events are an important cause of morbidity and mortality." - Anonymous Online Contributor
"Thrombus usually presents with dyspnea, pain and ischemia. Other signs include fever and erythrocyte disturbances. Thrombus on cardiac imaging is an important clue to the diagnosis of thrombus that requires urgent investigation with echocardiography. Followup of thrombosis should be considered in all patients presenting with thrombotic complications. Physicians must be aware of the signs of thrombus in the presentation of patients with a thrombus." - Anonymous Online Contributor
"Thrombus is generally associated with long-term disability and is often a cause for a myocardial infarction. The treatments for thrombus depend on the underlying disease, the anatomical position and physical symptoms.\n" - Anonymous Online Contributor
"Although the pathogenesis for thrombosis, deep-seated thrombosis in particular, is very complex, the optimal treatment still has not been identified with certainty. Many of the same considerations apply to other thromboses. There is no certainty that thrombus can be cured by any treatment modality." - Anonymous Online Contributor
"Aspirin 81mg ec tab is commonly used, but there is no clear evidence of the effect of the medication by itself compared to placebo in this setting. In this setting, more information is needed to clarify the role of aspirin itself." - Anonymous Online Contributor
"[Oxygen is needed by the cells in the intestines to form blood clots in order to stop bleeding. This is why patients must consume more oral dietary magnesium if they are taking aspirin. Magnesium binds and inactivates two of the three major enzymes involved in creating prothrombotic clots, which are ADP, PAI-1, and thrombin. Thus, patients taking aspirin should be taking dietary magnesium as well as taking supplemental vitamin B12, at least in the long term.](https://www.brit-wellorg"
"Chromide\n\nChromide is a common name for the chemical compounds and salts with the formula." - Anonymous Online Contributor
"Although the majority of our patients did not qualify for a trial, we consider prospective evaluation of patients who have thrombus to be an effective strategy for thrombotic disease." - Anonymous Online Contributor
"Recent findings does not provide evidence to support the hypothesis that 1.75 mg aspirin-eco [TC] is less effective at inhibiting thrombosis than either 6.25 or 81 mg aspirin-eco [IT]. This trial, in conjunction with other evidence, appears to indicate that aspirin-eco [IT] is as effective as the [IT] of other anti-platelet medications, such as clopidogrel." - Anonymous Online Contributor
"The clinical practice of performing ultrasonography in patients with a clinically suspected DVT or other peripheral vascular symptoms may increase the number of thrombi which may not be detected on a routine venous duplex scan. However, routine Doppler ultrasonography should always be performed in all patients for optimal patient management." - Anonymous Online Contributor
"Although the current trial does not include a [primary endpoint for the study comparing 81mg ec tab versus placebo in reducing the risk of ischemic stroke or [major adverse cardiovascular events], it is noteworthy that ischemic events occurred with significantly lower frequency than noted in clinical trials of high-dose aspirin and [aspirin 81mg ec tab]. This finding may be due to the lower dose used relative to the clinical trials reported in the medical literature. Because a lower-than-usual dose of aspirin is associated with reductions in cardiovascular, cardiovascular death, and all-cause mortality, including ischemic events, physicians were advised to provide patients with aspirin 81mg ec tab." - Anonymous Online Contributor