Dextrose Injection for Post-Traumatic Stress Disorder

Not yet recruiting at 3 trial locations
CR
Overseen ByClare R Solso, RN
Age: 18+
Sex: Any
Trial Phase: Phase 4
Sponsor: Dr. Dean Reeves Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

PTSD is a chronic mental health condition that drastically reduces an individual's quality of life Dextrose injection with a small needle has been used for chronic pain patients and observational results have shown it to be effective in reducing anxiety, brain fog, and depression in patients with PTSD. This randomized trial will compare dextrose injection with an injection control of normal saline (NS)

Who Is on the Research Team?

KD

Kenneth D Reeves, M.D.

Principal Investigator

Dr. Dean Reeves Clinic

Are You a Good Fit for This Trial?

This trial is for individuals with treatment-resistant PTSD who have tried at least two medications and two non-medication treatments without success. Participants should not be planning major surgery, taking daily narcotics, or consuming three or more alcoholic drinks per day. They must also have reliable transportation, be comfortable using computers, and not be involved in other PTSD studies.

Inclusion Criteria

No active suicidal plans
I do not have any major surgeries planned.
Reliable transportation
See 18 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive cervical plexus hydrodissection with D5W or normal saline at 0, 2, 4, and 8 weeks

8 weeks
4 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

3 months

Extension

Participants may request additional D5W treatment from 13-52 weeks

39 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cervical Plexus Hydrodissection

Trial Overview

The study is testing the effectiveness of injecting Dextrose 5% in water (D5W) versus Normal saline (NS) into the cervical plexus to alleviate symptoms of PTSD. This randomized trial aims to see if dextrose injections are better than saline injections for reducing anxiety, brain fog, and depression associated with PTSD.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: D5W cervical plexus hydrodissectionExperimental Treatment1 Intervention
Group II: Normal saline cervical plexus hydrodissectionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Dr. Dean Reeves Clinic

Lead Sponsor

Trials
5
Recruited
220+