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Antiplatelet Agent

Intervention Group for Hypertension (TAP Trial)

Phase 4

Waitlist Available

Led By Alisse K Hauspurg, MD

Research Sponsored by Alisse Hauspurg

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 to 6 months postpartum

Awards & highlights

TAP Trial Summary

"This trial aims to test if taking low-dose aspirin after preeclampsia in the immediate postpartum period can help improve blood vessel recovery. They will enroll up to 60 participants

Who is the study for?

This trial is for postpartum individuals over 18 who were diagnosed with preeclampsia. It's not open to those with pre-pregnancy hypertension or diabetes, allergies to aspirin, multiple gestations, fetal anomalies, or anyone who used aspirin during pregnancy.Check my eligibility

What is being tested?

The TAP Trial is testing if low-dose aspirin can help improve blood vessel function and lower blood pressure after preeclampsia. Participants will be randomly given either aspirin or a placebo and monitored through visits involving BP checks and other tests.See study design

What are the potential side effects?

Low-dose aspirin may cause side effects like gastrointestinal issues (like stomach pain), bleeding problems, allergic reactions in some people, but many take it without serious issues.

TAP Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 to 6 months postpartum

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 to 6 months postpartum

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 to 6 months postpartum for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent of participants eligible, enrolled and retained (feasibility)

Secondary outcome measures

Anti-hypertensive medication use

Change in diastolic blood pressure

Change in mean arterial pressure

+22 more

TAP Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Intervention GroupExperimental Treatment1 Intervention

Low-dose [81 mg] aspirin pill daily for 6 months will be given to subjects

Group II: Placebo GroupPlacebo Group1 Intervention

Similar appearing placebo pill daily for 6 months will be given to subjects.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Low-dose aspirin

2019

Completed Phase 2

~240

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Alisse HauspurgLead Sponsor

2 Previous Clinical Trials

170 Total Patients Enrolled

2 Trials studying Hypertension

170 Patients Enrolled for Hypertension

National Heart, Lung, and Blood Institute (NHLBI)NIH

3,841 Previous Clinical Trials

47,814,045 Total Patients Enrolled

469 Trials studying Hypertension

2,692,335 Patients Enrolled for Hypertension

Alisse K Hauspurg, MDPrincipal InvestigatorUPMC Magee Women's Hospital

1 Previous Clinical Trials

60 Total Patients Enrolled

1 Trials studying Hypertension

60 Patients Enrolled for Hypertension

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I meet the necessary criteria to participate in this research trial?

"Individuals aged 18 to 55 with a confirmed diagnosis of pre-eclampsia are eligible for enrollment in this study, which aims to recruit approximately 60 participants."

Answered by AI

What risks does the Intervention Group pose to participants?

"The safety of the Intervention Group in this Phase 4 trial is rated as a 3 by our team at Power, signifying that the treatment has been sanctioned for use."

Answered by AI

Is this clinical trial currently open for enrollment?

"Per clinicaltrials.gov, recruitment for this particular trial is presently closed. The study was initially posted on April 1, 2024, with the most recent update made on February 19, 2024. Despite its closure to new participants, there are currently 1409 other trials open and actively enrolling patients."

Answered by AI

Does this study include individuals who are older than 85 years of age?

"Patients aged between 18 and 55 years old meet the necessary requirements for participation in this trial. It is noteworthy that there are a total of 113 trials available for individuals under 18 years old, and as many as 1208 trials catering to those over the age of 65."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Treatment With Aspirin After Preeclampsia: TAP Trial

Alisse Hauspurg 2024. "Treatment With Aspirin After Preeclampsia: TAP Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06281665.

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