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Buprenorphine Microdosing for Opioid Use Disorder (Micro-bupe Trial)
Micro-bupe Trial Summary
This trial will compare the effects of two different methods of starting buprenorphine treatment - a microdose induction and the usual treatment protocol.
Micro-bupe Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowMicro-bupe Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Micro-bupe Trial Design
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Who is running the clinical trial?
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- I am currently being treated for opioid use disorder.I am fluent in English or Spanish.I will be in the hospital for at least 2 days.You have a serious mental illness that has not been treated. This includes thoughts of suicide or experiencing psychosis.I am currently using opioid medication.I experience chronic pain.I experience pain because of my cancer.You have a history of misusing opioids or have opioid use disorder.You have a serious problem with alcohol or benzodiazepine use.I am allergic to BUP or naloxone.I am older than 18 years.
- Group 1: Treatment As Usual (TAU)
- Group 2: BUP microdose induction
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many individuals are being accepted into this experimental research?
"Affirmative. The entry posted on clinicaltrials.gov reveals that this medical research is actively enrolling participants, with the first post made on August 29th 2022 and most recent update on September 28th 2022. This trial seeks to recruit a total of 270 individuals at one study site."
Is BUP microdose induction a safe method of therapy for patients?
"BUP microdose induction has been approved for use, so its safety rating on our scale of 1 to 3 is a solid 3."
Is this investigation presently open to participants?
"According to clinicaltrials.gov, this medical experiment was initially posted on August 29th 2022 and its recruitments are still ongoing; the most recent update being dated September 28th 2022."
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