High-level construal for Cancer

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Cancer+2 MoreHigh-level construal - Behavioral
Eligibility
25 - 55
All Sexes
What conditions do you have?
Select

Study Summary

This trial is researching whether a new treatment for smoking cessation, called high-level construal, is effective. The study will compare high-level construal to a standard text-messaging intervention to see if it results in fewer cigarettes smoked per day.

Eligible Conditions
  • Smoking Cessation
  • Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

6 Primary · 2 Secondary · Reporting Duration: Within two weeks of enrollment

Day 56
Nerve Block
Aim 2: Degree of prediction success of change in smoking from surveys
Aim 2: Prediction success of change in smoking from task data
Aim 3: Effect size of high-level construal on smoking at endpoint
At baseline
Aim 1: Neural similarity at baseline among the proposed psychological mechanisms
Day 1
Aim 3: Time-series of the effect size of high-level construal on smoking across the training period
Within two weeks of enrollment
Aim 2: Correlation of pattern representation of high-level construal with survey measure
Aim 2: Prediction of craving ratings from multivariate representations of high-level construal

Trial Safety

Trial Design

4 Treatment Groups

Effortful down-regulation of craving for cigarettes
1 of 4
Up-regulation of goal energization
1 of 4
High-level construal
1 of 4
Treatment-as-usual control
1 of 4

Experimental Treatment

Non-Treatment Group

240 Total Participants · 4 Treatment Groups

Primary Treatment: High-level construal · Has Placebo Group · N/A

Effortful down-regulation of craving for cigarettes
Behavioral
Experimental Group · 1 Intervention: Down-regulation of craving for cigarettes · Intervention Types: Behavioral
Up-regulation of goal energization
Behavioral
Experimental Group · 1 Intervention: Up-regulation of goal energization · Intervention Types: Behavioral
High-level construal
Behavioral
Experimental Group · 1 Intervention: High-level construal · Intervention Types: Behavioral
Treatment-as-usual control
Behavioral
PlaceboComparator Group · 1 Intervention: Treatment-as-usual control · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: within two weeks of enrollment

Who is running the clinical trial?

University of OregonLead Sponsor
68 Previous Clinical Trials
34,466 Total Patients Enrolled
Ohio State UniversityOTHER
712 Previous Clinical Trials
463,674 Total Patients Enrolled
Elliot T Berkman, Ph.D.Principal InvestigatorUniversity of Oregon

Eligibility Criteria

Age 25 - 55 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
? Are you someone who's tried to quit smoking, but failed each time? You're not alone
This means that the household's income, adjusted for their household size, is below the federal poverty line.
Cigarette smokers who smoke at least 10 cigarettes per day for at least 2 years are considered to be persistent smokers.
References