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Vaccine + Chemoradiation for Cervical Cancer
Study Summary
This trial is studying a vaccine given with chemotherapy and radiation to treat patients with cervical cancer.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Media Library
- I have had a therapeutic HPV vaccine, not just the preventive ones like Gardasil.I have had hepatitis B or C but am cured of hepatitis C.I have had chemotherapy for cervical cancer.I haven't received immunotherapy or biological response modifiers in the last 4 weeks.I had major surgery less than 4 weeks ago and haven't fully recovered.I am not allergic to the trial medication and do not have severe nerve damage or hearing loss.I am currently using or have recently used corticosteroids in forms like creams, inhalers, or injections into joints.I have a history of significant autoimmune disease or inflammatory bowel disease.You have another health condition or have undergone previous treatments that could negatively affect your well-being or make it difficult to accurately interpret the study results.I have no other cancers except for treated skin cancer, or I've been cancer-free from another type for 5 years.I haven't taken high doses of steroids or immunosuppressants in the last week.I have had a hysterectomy or will have one as part of my cervical cancer treatment.I have been recently diagnosed with advanced cervical cancer.I have had radiation therapy in the pelvic area before.I can take care of myself and perform daily activities.I have a condition that affects my immune system.I have been diagnosed with squamous cell cervical cancer.
- Group 1: Treatment (radiation therapy, cisplatin, PDS0101)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any empty enrolment slots left in this experiment?
"Yes, an online search confirms that this study is recruiting patients. The posting date was October 14th 2020, and the clinical trial has been updated as recently as March 31st 2022. They are searching for a total of 35 patients from 1 medical site."
What condition does the Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101 help patients with?
"The liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101 is most frequently used to treat neoplasm metastasis. In addition, this medication can be given to patients with refractory advanced ovarian cancer or who have an advance directive in place."
How many people have signed up to take part in this research project?
"Yes, the trial is recruiting patients. According to clinicaltrials.gov, the study was posted on October 14th 2020 and was last edited on March 31st 2022. The research team needs to recruit 35 individuals from 1 site."
Are there any other similar clinical trials to the Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101?
"Currently, there are 773 active studies examining the Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101. The majority of these trials (300) are in Phase 3. Additionally, most of the clinical trials for this vaccine are being conducted in Shanghai, China. However, there are a total of 44169 locations running trials for the Liposomal HPV-16 E6/E7 Multipeptide Vaccine PDS0101."
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