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Prazosin for Post-Traumatic Stress Disorder (PREDICT Trial)
PREDICT Trial Summary
This trial is testing whether two simple tests can predict whether someone with PTSD will respond to the medication prazosin.
PREDICT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 4 trial • 20 Patients • NCT02199652PREDICT Trial Design
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Who is running the clinical trial?
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- I have been diagnosed with PTSD.I do not have a major psychiatric or neurocognitive disorder like schizophrenia or Alzheimer's.I haven't taken certain blood pressure or sleep medications in the last week and am willing to avoid them during the study.I am a woman who can become pregnant and agree to use birth control or abstain from sex during the study.I have been diagnosed with PTSD.
- Group 1: Open label, blinded discontinuation, prazosin, placebo
- Group 2: Open label, blinded discontinuation, placebo, prazosin
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who meets the qualifications to participate in this research?
"The desired participants for this trial must have a diagnosis of post-traumatic stress disorder and be within the age brackets of 21 to 75. A total of 70 individuals are needed for the study."
Is this clinical trial open to patients who are younger than 85 years old?
"In order to qualify for this study, patients must be aged 21-75. Out of the 488 total clinical trials taking place, 46 are specifically for minors and 342 are for adults over 65."
What are Prazosin's common therapeutic benefits?
"Prazosin is a medication that is most often used to manage symptoms of post-traumatic stress disorder. Additionally, it can be effective in treating conditions such as nightmares, hypertensive disease, and benign prostatic hyperplasia."
Are there other Prazosin studies that have been completed?
"There are seven ongoing clinical trials studying Prazosin. One of these live studies is in Phase 3, with the rest being conducted primarily in Seattle, Washington. In total, there are nine locations running research for this treatment."
Has Prazosin undergone the FDA's drug approval process?
"Prazosin received a safety score of 3 because there is both efficacy and safety data from Phase 3 trials."
What is the total number of individuals enrolled in this experiment?
"That is right, the clinicaltrials.gov website has information indicating that this trial is currently looking for subjects. The study was first advertised on 6/4/2018 and updated as recently as 4/1/2022. They are hoping to find 70 patients from 1 location."
Are new enrollees still being taken in for this research project?
"Yes, this trial is currently recruiting patients. The study was first posted on June 4th, 2018 and the most recent update was April 1st, 2022."
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