Oral Tranexamic Acid for Shoulder Replacement Surgery
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are taking anticoagulants (blood thinners) other than aspirin.
What data supports the effectiveness of the drug Tranexamic Acid for shoulder replacement surgery?
Research shows that Tranexamic Acid can reduce blood loss and the need for blood transfusions during and after shoulder replacement surgery. It has been effective in similar surgeries, like knee and hip replacements, and studies indicate it helps decrease blood volume loss and changes in blood levels during shoulder surgeries.12345
Is oral tranexamic acid safe for humans?
How is the drug tranexamic acid unique for shoulder replacement surgery?
Tranexamic acid is unique for shoulder replacement surgery because it helps reduce blood loss during and after the procedure, which can decrease the need for blood transfusions. Unlike other treatments, it specifically targets the reduction of blood loss by preventing the breakdown of blood clots, making it particularly useful in surgeries where bleeding is a concern.12458
What is the purpose of this trial?
The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid
Research Team
Walter Smith
Principal Investigator
University of Alabama at Birmingham
Eligibility Criteria
This trial is for patients who are scheduled to undergo total shoulder arthroplasty, which is a type of shoulder replacement surgery. Specific eligibility criteria have not been provided.Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive an extended postoperative course of oral tranexamic acid following total shoulder arthroplasty
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Tranexamic Acid
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor