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Chlorhexidine vs Calcium Hydroxide for Tooth Pain
Study Summary
This trial will compare two treatments for tooth pain to find which is better at reducing pain between dentist visits.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 2 trial • 44 Patients • NCT02252588Trial Design
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Who is running the clinical trial?
Media Library
- I speak English or Spanish.I have a tooth that can be fixed.I need a root canal treatment.I feel pain in my tooth when I bite down.I have a tooth that can be fixed.I need a root canal treatment.I speak English or Spanish.I have a cracked tooth.I have pain in my tooth when I bite down.I am 18 years old or older.I have a tooth that cannot be fixed.I haven't taken any pain medication or antibiotics in the last 3 days.
- Group 1: Clorhexidine
- Group 2: Calcium Hydroxide
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are seniors eligible to participate in the current trials for this treatment option?
"This trial has an age range of 18 to 80 years old, meaning the lower and upper limit are respectively set at the legal age of consent and octogenarian status."
What adverse effects have been noted with Clorhexidine use?
"Our risk assessment team gave Clorhexidine a rating of 3 due to the evidence provided by Phase 3 clinical trials demonstrating its efficacy and safety."
Who meets the criteria to participate in this experimental research?
"To meet the qualifications for this trial, patients need to be diagnosed with apical periodontitis and between 18-80 years of age. Approximately 40 individuals will receive admission into the study."
What are the most common ailments that Clorhexidine is employed to address?
"Clorhexidine is a common and effective remedy for antisepsis, as well as disinfection of the throat area, minor cuts and scrapes, and pressure ulcers."
How many participants are currently involved in this research project?
"This experiment is currently not seeking participants, as per its last update on March 6th 2023. If you are in search of alternate studies, there are 88 trials recruiting individuals with apical periodontitis and 23 clinical tests that need volunteers for Clorhexidine research."
Has Clorhexidine been tested before in a clinical setting?
"As of now, 23 experiments related to the efficacy of Clorhexidine are being conducted. Six trials have reached Phase 3 and 96 clinical sites across the country are taking part in its research. The major concentration is in Los Angeles, California."
Are there any vacancies left in this research program?
"According to the details listed on clinicaltrials.gov, this research is no longer seeking patients; it was initially posted on May 30th 2023 and last updated in March 6th 2023. Nonetheless, there are 111 other trials currently recruiting participants at the moment."
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