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semaglutide 2.4 mg for Obesity
Study Summary
This trial is comparing the effect of semaglutide to a placebo on weight and pain in obese patients with knee pain. It will last for 1.5 years and has 14 clinic visits.
- Obesity
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- Group 1: semaglutide 2.4 mg
- Group 2: semaglutide 2.4 mg (placebo)
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are some of the key conditions that semaglutide 2.4 mg has been shown to improve?
"Semaglutide 2.4 mg is frequently used to help patients manage their weight over the long term. However, it can also be used as part of a treatment plan that includes a reduced-calorie diet, exercise, and managing at least one other weight-related condition."
Can you please list any other investigations that have included semaglutide 2.4 mg?
"The first semaglutide 2.4 mg clinical trial was completed in 2018 at the Novo Nordisk Investigational Site. So far, 123 trials have been completed in total. There are currently 59 actively recruiting trials, with a large number of these studies taking place in Saint Louis, Missouri."
Does this research differ from other similar investigations?
"Since 2018, semaglutide 2.4 mg has been the subject of clinical research with the first trial sponsored by Novo Nordisk A/S. The Phase 4 drug approval was received following the first study in 2018, which involved 1387 patients. As of now, there are 59 live studies being conducted for semaglutide 2.4 mg across 711 cities in 55 countries."
Why did researchers start this clinical trial?
"The pharmaceutical company leading this study, Novo Nordisk A/S, has announced that the primary outcome will be change in body weight from the start of the study (week 0) to the end of treatment (week 68). Additionally, this trial will be measuring if patients achieve a 5% or greater reduction in body weight (yes/no), change in pain medication (dose), and change in WOMAC stiffness score (points)."
What are the FDA's most recent thoughts on semaglutide 2.4 mg?
"Semaglutide 2.4 mg is in Phase 3 clinical trials, signifying that while there is efficacy data, there are also multiple rounds of safety data. Because of this, our team has given it a score of 3."
Are there any available appointments for this clinical trial?
"This specific trial is not enrolling patients at the moment, as indicated by the clinicaltrials.gov website. The listing was created on October 1st, 2021 and was last edited June 21st, 2022. Even though this trial has closed recruitment, there are 1,754 other trials that are still recruiting patients."
Who else is applying?
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What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
What questions have other patients asked about this trial?
How responsive is this trial?
Most responsive sites:
- Novo Nordisk Investigational Site: < 48 hours
Average response time
- < 2 Days
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