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Stereotactic Radiosurgery for Brain Metastasis
Study Summary
This trial is investigating whether stereotactic radiosurgery, which only targets areas of the brain affected by the disease, is better than whole brain radiation therapy at preserving brain function in small cell lung cancer patients with brain metastasis.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check βYesβ for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2019 Phase 2 trial β’ 32 Patients β’ NCT01573702Trial Design
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Who is running the clinical trial?
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- I do not have a history of metastatic cancer other than small cell, or any uncontrolled non-metastatic cancer.I do not have a psychiatric or neurological illness affecting my thinking, except if it's due to brain metastasis.My doctor has assessed my ability to perform daily activities.You cannot participate if tests find cancer cells in your spinal fluid.My diagnosis of small cell lung cancer is confirmed through tissue samples.Having circulating tumor DNA in the cerebrospinal fluid (CSF) does not prevent participation in the study.You cannot participate if tests show that you have leptomeningeal disease.I am not pregnant or breastfeeding.I can take care of myself but may not be able to do heavy physical work.I have not had radiation therapy to my brain.I have 10 or fewer brain tumors, confirmed by a recent MRI.All my cancer lesions can be treated with targeted radiation.Your blood clotting test should show normal results within 28 days before joining the study.
- Group 1: Treatment (SRS)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there still openings available for this clinical experiment?
"As per records on clinicaltrials.gov, this medical experiment is still recruiting participants after its initial posting date of August 28th 2020 and subsequent update on June 8th 2022."
How many participants are being monitored in this research endeavor?
"Affirmative, the information posted on clinicaltrials.gov indicates that this medical trial is actively recruiting patients. It was first published on August 28th 2020 and has recently been updated as of June 8th 2022. The study requires 50 participants at one location."
Has the FDA sanctioned Stereotactic Radiosurgery?
"There is some evidence that suggests Stereotactic Radiosurgery's safety, which has earned it a score of 2. However, there lacks any data proving efficacy in this Phase 2 trial."
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