Image-Guided Radiosurgery for Brain Tumor
(IG-SRS Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial uses advanced imaging and precise radiation treatment to help adult patients with 1 to 3 brain metastases. It aims to protect important brain areas during treatment, preserving cognitive functions like memory and attention.
Who Is on the Research Team?
Jona Hattangadi-Gluth, MD
Principal Investigator
University of California, San Diego
Are You a Good Fit for This Trial?
Adults over 18 with 1-3 small brain metastases from cancers like lung or breast, who can undergo MRI scans and have a life expectancy over 6 months. They must be able to perform daily activities with mild symptoms at most and participate in neurocognitive tests. Pregnant women, those unable to use contraception, or patients previously treated with whole brain radiation are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo MRI with DTI and 3D volumetric imaging and a battery of neurocognitive tests
Treatment
Participants receive cognitive-sparing brain SRS with advanced imaging techniques
Follow-up
Participants are monitored for cognitive performance and imaging biomarkers at 1, 3, and 6 months post-treatment
What Are the Treatments Tested in This Trial?
Interventions
- Cognitive Sparing Brain Stereotactic Radiosurgery (SRS)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Jona Hattangadi-Gluth
Lead Sponsor
National Cancer Institute (NCI)
Collaborator
National Institutes of Health (NIH)
Collaborator