Ga-68-DOTATATE vs. Ga-68-DOTATOC PET Scans for Meningioma
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is evaluating different imaging scans to determine which one is more effective in detecting brain tumors in patients with meningioma. The scans use substances that make the tumors more visible, aiding doctors in their diagnosis.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is Ga-68-DOTATATE or Ga-68-DOTATOC safe for use in humans?
How is the treatment with Ga-68-DOTATATE and Ga-68-DOTATOC different from other treatments for meningioma?
Ga-68-DOTATATE and Ga-68-DOTATOC are unique because they are used in PET scans to better visualize meningiomas by targeting somatostatin receptors, which are often present in these tumors. This approach helps in more precise radiation treatment planning compared to traditional MRI, potentially leading to smaller radiation volumes and improved detection of tumor areas.12367
What data supports the effectiveness of the drug Ga-68-DOTATATE for meningioma?
Research shows that Ga-68-DOTATATE PET scans can help in detecting and planning treatment for meningiomas, especially when combined with MRI, leading to better identification of tumor areas and more precise radiation treatment. This drug has been found to be more sensitive and specific than MRI alone, aiding in the detection of recurrent meningioma and improving treatment outcomes.12368
Who Is on the Research Team?
Jana Ivanidze, MD/PhD
Principal Investigator
Weill Medical College of Cornell University
Are You a Good Fit for This Trial?
This trial is for adults who are suspected to have meningioma and are preparing for surgery. They must be able to lie still on a scanner table and not have any reasons they can't receive the radiotracers being tested.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Imaging Comparison
Direct comparison of Ga-68-DOTATATE and Ga-68-DOTATOC PET/CT in patients with meningioma
Surgical Resection and Biomarker Analysis
Patients undergo surgical resection of the lesion and biomarker analysis is performed
Follow-up
Participants are monitored for safety and effectiveness after imaging and surgical procedures
What Are the Treatments Tested in This Trial?
Interventions
- Ga-68-DOTATATE
- Ga-68-DOTATOC
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor
Cornell University
Collaborator