SBRT for Non-Small Cell Lung Cancer

Phase-Based Progress Estimates
Rhode Island Hospital, Providence, RINon-Small Cell Lung CancerSBRT - Radiation
All Sexes
What conditions do you have?

Study Summary

This trial will test a combination of therapies for stage IB-III non-small cell lung cancer. If successful, it could become a new standard of care for this disease.

Eligible Conditions
  • Non-Small Cell Lung Cancer

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: From beginning of study treatment to approximately day 49-63 on study.

Day 90
Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability]
Day 49
Number of Patients with a Pathologic Response

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

1 Treatment Group

Protocol Therapy
1 of 1

Experimental Treatment

25 Total Participants · 1 Treatment Group

Primary Treatment: SBRT · No Placebo Group · Phase 2

Protocol TherapyExperimental Group · 3 Interventions: SBRT, Ipilimumab, Nivolumab · Intervention Types: Radiation, Drug, Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
Completed Phase 3
FDA approved
FDA approved

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: from beginning of study treatment to approximately day 49-63 on study.

Who is running the clinical trial?

Brown UniversityLead Sponsor
421 Previous Clinical Trials
521,729 Total Patients Enrolled
Bristol-Myers SquibbIndustry Sponsor
2,514 Previous Clinical Trials
3,945,315 Total Patients Enrolled
Christopher G Azzoli, MDPrincipal InvestigatorBrown University
Thomas A DiPetrillo, MDPrincipal InvestigatorBrown University

Eligibility Criteria

Age 18+ · All Participants · 15 Total Inclusion Criteria

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Frequently Asked Questions

How many people are being asked to participate in this clinical trial?

"That is correct. As of February 22nd, 2022, this clinical trial was still recruiting patients that had first been posted about on October 5th, 2021. They are seeking 25 individuals from 1 medical location." - Anonymous Online Contributor

Unverified Answer

What is the history of Ipilimumab in research?

"Ipilimumab is being researched in 796 clinical trials, 86 of which are currently active. The many Phase 3 studies for Ipilimumab primarily take place in Pittsburgh, Pennsylvania; however, there are 43300 locations running these sorts of trials." - Anonymous Online Contributor

Unverified Answer

What are the conditions Ipilimumab is used to treat?

"Treatments that can be administered using Ipilimumab include anti-angiogenic therapy, malignant neoplasms, and unresectable melanoma." - Anonymous Online Contributor

Unverified Answer

Are volunteers still being sought for this experiment?

"Based on the information available on, it appears that this study is still recruiting patients. The trial was first posted on 10/5/2021 and was last updated on 2/22/2022. They are looking for a total of 25 participants from 1 site." - Anonymous Online Contributor

Unverified Answer

Could you explain the possible risks associated with Ipilimumab?

"While there is data supporting Ipilimumab's safety, it garnered a score of 2 because there is no evidence backing its efficacy." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.