PRM-125 for High Blood Pressure
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new treatment called PRM-125, an experimental drug, to evaluate its effectiveness in lowering blood pressure in individuals with hypertension. The goal is to determine if taking PRM-125 once daily can effectively manage hypertension. Individuals with primary hypertension and no other medical conditions that could interfere with the study may be suitable candidates. As a Phase 3 trial, this study represents the final step before FDA approval, offering participants the opportunity to contribute to a potentially groundbreaking treatment for hypertension.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is there any evidence suggesting that PRM-125 is likely to be safe for humans?
Research has shown that PRM-125 was tested in earlier trials to assess its safety for people. Results so far suggest that patients generally tolerate PRM-125 well. These studies reported no serious side effects, indicating a positive safety profile.
The current trial is in a late stage, meaning earlier studies provided enough evidence to suggest that PRM-125 is safe for testing on more people. Researchers typically conduct this phase when they are confident about a treatment's safety.
The available data has revealed no specific safety concerns or harmful effects. This suggests that PRM-125 may be a safe option for people with high blood pressure, although ongoing studies continue to monitor its safety closely.12345Why do researchers think this study treatment might be promising for hypertension?
PRM-125 is unique because it targets ambulatory blood pressure in a new way that might offer benefits over standard treatments like ACE inhibitors or beta-blockers. It has a different mechanism of action, potentially allowing for better control of blood pressure throughout the day without the peaks and valleys seen with current medications. Researchers are excited about PRM-125 because it could improve patient compliance and overall cardiovascular health by providing more consistent blood pressure management.
What evidence suggests that PRM-125 might be an effective treatment for hypertension?
Research suggests that PRM-125, the investigational treatment in this trial, might help manage high blood pressure. Although specific information about its effects on high blood pressure remains limited, PRM-125 has shown positive results in other areas. For instance, it has improved sleep quality and how people feel upon waking. These benefits might enhance overall well-being, hinting at a possible advantage for high blood pressure. While more direct evidence is needed, these early findings offer a hopeful view of PRM-125's potential to lower blood pressure.678910
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive PRM125 once daily for 8 weeks to evaluate changes in ambulatory blood pressure
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- PRM-125
Find a Clinic Near You
Who Is Running the Clinical Trial?
PRM Pharma, LLC
Lead Sponsor