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DOAC vs Warfarin as Blood Thinners After Heart Surgery (DANCE Trial)
DANCE Trial Summary
This trial is comparing the safety of two types of blood thinners in the early days after heart surgery.
DANCE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowDANCE Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.DANCE Trial Design
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Who is running the clinical trial?
Media Library
- I have not had open heart surgery in the last 10 days.It's not possible to keep in touch with you after the study.My kidneys are not working well (creatinine clearance <30 ml/min).I have been diagnosed with triple-positive antiphospholipid syndrome.I do not have severe liver disease.I have had heart surgery, including a device implant or heart transplant.I have atrial fibrillation and need blood thinners.I cannot take certain blood thinners due to health reasons.I have a condition that causes ongoing bleeding or easy bruising.You have a mechanical heart valve.I am pregnant, breastfeeding, or able to become pregnant.I am 18 years old or older.
- Group 1: Vitamin K Antagonist
- Group 2: Direct Oral Anticoagulation (DOAC)
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 20 Other Conditions - This treatment demonstrated efficacy for 20 other conditions.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What other clinical trials have included DOACs in their research?
"There are currently 124 ongoing clinical trials researching Direct Oral Anticoagulation (DOAC), with 45 of those in Phase 3. Clayton, Victoria is home to the majority of these trials; however, there are 2460 locations running studies for Direct Oral Anticoagulation (DOAC) worldwide."
Has the FDA cleared Direct Oral Anticoagulation (DOAC) for use?
"DOACs have Phase 3 clinical trial data supporting their efficacy and multiple rounds of data attesting to their safety, so they received a score of 3."
What conditions are usually treated with Direct Oral Anticoagulation (DOAC)?
"Direct Oral Anticoagulation (DOAC) is an effective method for treating patients with conditions like vitamin k, cerebrovascular accident, and systemic embolism."
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