Insulin Detemir vs NPH for Gestational Diabetes
(DETERMINE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of the study is to compare rates of neonatal hypoglycemia with maternal NPH vs determir use.
Do I have to stop taking my current medications for the trial?
The trial does not specify if you need to stop taking your current medications, but it involves using insulin detemir or NPH for managing blood sugar during pregnancy.
Is insulin detemir safe for use in pregnant women with diabetes?
How does insulin detemir differ from NPH insulin for gestational diabetes?
What data supports the effectiveness of the drug Insulin Detemir for gestational diabetes?
Who Is on the Research Team?
Christina S Han, MD
Principal Investigator
University of California, Los Angeles
Michael Richley, MD
Principal Investigator
University of California, Los Angeles
Are You a Good Fit for This Trial?
This trial is for pregnant women with Type 2 or gestational diabetes needing insulin. It's not for those under 18, with a planned early delivery, pre-pregnancy insulin use, type 1 diabetes, HIV/Hepatitis infections, fetal malformations, kidney/liver issues, or expecting multiples.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either insulin detemir or insulin NPH to control blood sugars during pregnancy
Follow-up
Participants are monitored for safety and effectiveness after treatment, including neonatal outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Insulin Detemir
- Insulin NPH
Insulin Detemir is already approved in European Union, United States, Canada, Japan for the following indications:
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Los Angeles
Lead Sponsor