Post-Stroke Monitoring Strategies for Ischemic Stroke
Trial Summary
What is the purpose of this trial?
OPTIMISTmain is an investigator-initiated and conducted, international, multicentre, stepped wedge cluster randomized controlled trial comparing the effects of different intensities of nursing care monitoring for patients with acute ischemic stroke of mild severity and without critical care needs after IV-tPA.
Do I need to stop my current medications for this trial?
The trial protocol does not specify whether you need to stop taking your current medications. Please consult with the trial coordinators for more details.
What data supports the idea that Post-Stroke Monitoring Strategies for Ischemic Stroke is an effective treatment?
The available research shows that effective management of ischemic stroke involves prompt assessment and monitoring of vital signs like blood pressure and oxygen levels. This helps in early detection of complications and improves patient outcomes. While the research highlights the importance of organized stroke services and early interventions like aspirin and intravenous treatments, it emphasizes that close monitoring is crucial to detect any early signs of deterioration. This supports the idea that Post-Stroke Monitoring Strategies are effective in managing ischemic stroke.12345
What safety data exists for post-stroke monitoring strategies for ischemic stroke?
The provided research does not directly address safety data for specific post-stroke monitoring strategies like 'Guideline recommended standard monitoring,' 'Low-intensity monitoring strategy,' or 'Optimal Post Tpa-Iv Monitoring.' However, the studies emphasize the importance of evidence-based guidelines for secondary prevention and management of ischemic stroke, including antiplatelet therapy and risk factor control. The Liverpool Heart And bRain Project (L-HARP) aims to investigate cardiovascular outcomes and risk factors post-stroke, which may indirectly contribute to understanding safety in monitoring strategies. Further specific studies would be needed to evaluate the safety of these particular monitoring strategies.678910
Is the treatment 'Guideline recommended standard monitoring' a promising treatment for post-stroke monitoring in ischemic stroke?
Yes, 'Guideline recommended standard monitoring' is a promising treatment for post-stroke monitoring in ischemic stroke. It helps in preventing future strokes by controlling risk factors and using appropriate therapies. This approach is based on expert recommendations and evidence, aiming to improve patient outcomes.711121314
Research Team
Victor C Urrutia, MD
Principal Investigator
Johns Hopkins University
Craig S Anderson, MD PhD
Principal Investigator
The George Institute
Eligibility Criteria
This trial is for adults over 18 who've had a mild to moderate ischemic stroke and received IV alteplase treatment. They should be stable without needing intensive care after the infusion. It's not for those with major neurological issues or specific reasons they can't have standard or low-intensity monitoring.Inclusion Criteria
Exclusion Criteria
Treatment Details
Interventions
- Guideline recommended standard monitoring
- Low-intensity monitoring strategy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Craig Anderson
Lead Sponsor
Johns Hopkins University
Collaborator
Genentech, Inc.
Industry Sponsor
Ashley Magargee
Genentech, Inc.
Chief Executive Officer since 2024
MBA from Harvard University, BA from Princeton University
Levi Garraway
Genentech, Inc.
Chief Medical Officer since 2021
MD, PhD
The George Institute for Global Health, Australia
Collaborator