Proton Radiotherapy for Liver Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This phase II trial studies the effect of stereotactic body proton radiotherapy in treating patients with liver cancer. Proton radiotherapy is a type of treatment that uses high-energy beams to treat tumors.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.
Is proton radiotherapy safe for liver cancer?
How is Proton Stereotactic Body Radiation Therapy different from other treatments for liver cancer?
Proton Stereotactic Body Radiation Therapy (SBRT) for liver cancer is unique because it uses proton beams, which can deliver high doses of radiation directly to the tumor while minimizing damage to surrounding healthy tissues. This is particularly beneficial for liver cancer, as it helps protect the liver and other nearby organs from unnecessary radiation exposure.12678
What data supports the effectiveness of Proton Stereotactic Body Radiation Therapy for liver cancer?
Research suggests that proton therapy, including stereotactic body proton radiotherapy, can be effective for liver cancer by targeting tumors precisely and sparing healthy tissue. Studies have shown it to be safe and potentially beneficial for patients with liver cancer, although there are challenges in its implementation.128910
Who Is on the Research Team?
Jonathan B Ashman, M.D.
Principal Investigator
Mayo Clinic
Are You a Good Fit for This Trial?
Adults with newly diagnosed or recurrent liver cancer, specifically hepatocellular carcinoma without metastases. They can have up to three treatable lesions and may have had prior local treatments. Participants should be in relatively good health (ECOG 0-2), with a life expectancy of at least 3 months, adequate blood counts, and no severe illnesses that could interfere with the study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo 1 SBPT fraction over 20-30 minutes per day for a total of 5 fractions
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Proton Stereotactic Body Radiation Therapy
Find a Clinic Near You
Who Is Running the Clinical Trial?
Mayo Clinic
Lead Sponsor
National Cancer Institute (NCI)
Collaborator