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High Dose Radiation vs Whole Brain Radiation for Brain Metastasis
This trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus for the treatment of small cell lung cancer that has spread to the brain.
- Brain Metastasis
- Lung Cancer
- Small Cell Lung Cancer
Inclusion CriteriaYou will be eligible if you check “Yes” for the criteria below
Study ObjectivesOutcome measures can provide a clearer picture of what you can expect from a treatment.
Awards & Highlights
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Who is running the clinical trial?
- Group 1: Arm I (SRS)
- Group 2: Arm II (HA-WBRT, memantine)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What are other examples of research using Stereotactic Radiosurgery?
"First observed in 1997 at Vanderbilt University's Autonomic Dysfunction Center, Stereotactic Radiosurgery has been the focus of 122 clinical trials. Out of these, 27 are still active. Maryland's Easton location has a high concentration of these ongoing studies."
Has Stereotactic Radiosurgery been cleared by the FDA?
"There is some efficacy data and multiple rounds of safety data, so our team has rated the safety of Stereotactic Radiosurgery as a 3."
Are we currently enrolling patients for this experiment?
"Yes, this information is accurate. The trial was posted on 24 March 2021 and was updated on 8 April 2022."
How many individuals are being monitored for this research?
"That is correct. The clinical trial is recruiting at 82 locations and is looking for a total of 200 participants. The original posting was on 2021-03-24, with the most recent update on 2022-04-08."
Do a lot of hospitals in Canada offer this treatment?
"So far, 82 patients have enrolled at this clinical trial's various locations, which include the University of Maryland Shore Medical Center at Easton in Easton, Saint Mary Mercy Hospital in Livonia, and Missourif Maryland Shore Medical Center at Easton in Easton, Saint Mary Mercy Hospital in Livonia, and Missouri Baptist Outpatient Center-Sunset Hills in Sunset Hills."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
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