Levocetirizine (LTZ) for Allergic Asthma

Phase-Based Progress Estimates
Children's Mercy Hospital, Kansas City, MOAllergic AsthmaLevocetirizine Dihydrochloride - Drug
6 - 17
All Sexes
What conditions do you have?

Study Summary

This trial is testing whether the medication Levocetirizine can help improve asthma control in children who have uncontrolled persistent allergic asthma, and who are either hyperresponsive or hyporesponsive to histamine. The trial will compare results between African American/Black and Caucasian/White children.

Eligible Conditions
  • Asthma, Allergic

Treatment Effectiveness

Effectiveness Progress

2 of 3
This is further along than 85% of similar trials

Study Objectives

1 Primary · 2 Secondary · Reporting Duration: 6 weeks

6 weeks
Asthma exacerbation rates
Asthma related quality of life
Therapeutic response to antihistamine

Trial Safety

Safety Progress

3 of 3
This is further along than 85% of similar trials

Trial Design

2 Treatment Groups

Levocetirizine (LTZ)
1 of 2
1 of 2

Active Control

Non-Treatment Group

300 Total Participants · 2 Treatment Groups

Primary Treatment: Levocetirizine (LTZ) · Has Placebo Group · Phase 3

Levocetirizine (LTZ)
ActiveComparator Group · 1 Intervention: Levocetirizine Dihydrochloride · Intervention Types: Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 6 weeks

Who is running the clinical trial?

Children's Mercy Hospital Kansas CityLead Sponsor
226 Previous Clinical Trials
1,269,355 Total Patients Enrolled
1 Trials studying Asthma, Allergic
211 Patients Enrolled for Asthma, Allergic
National Institutes of Health (NIH)NIH
2,471 Previous Clinical Trials
24,591,248 Total Patients Enrolled
2 Trials studying Asthma, Allergic
185 Patients Enrolled for Asthma, Allergic

Eligibility Criteria

Age 6 - 17 · All Participants · 7 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You are currently receiving treatment for asthma according to guidelines.

Frequently Asked Questions

How many people are meeting the requirements for this clinical trial?

"Yes, the trial is still recruiting patients. According to the information on clinicaltrials.gov, this study was first posted on 4/28/2021 and was last updated on 4/26/2022. They are looking for 300 patients from 1 site." - Anonymous Online Contributor

Unverified Answer

How do I sign up for this test?

"This trial is looking for 300 participants with asthma and allergies between the ages of 6 and 17. The most important criteria for candidates are as follows: A diagnosis of asthma from a physician, uncontrolled asthma based on Asthma Control Test (ACT) score in the last 3 months or at screening, evidence of allergic sensitization from allergy skin test or allergy blood test results, currently being treated with asthma guideline-based therapy, males and females 6 through 17 years old at time of enrollment, written permission/assent to participate, children who self-identify as African American/black or Caucasian/white." - Anonymous Online Contributor

Unverified Answer

Has the FDA given the okay to market Levocetirizine?

"Levocetirizine has been studied in multiple Phase 3 clinical trials, which provides evidence of both its efficacy and safety. Therefore, our team at Power rates the safety of Levocetirizine as a 3 on our scale." - Anonymous Online Contributor

Unverified Answer

Are there any other ongoing research projects that include Levocetirizine?

"At this time, there are 2 clinical trials underway for Levocetirizine (LTZ). 1 of those is currently in Phase 3. The majority of the research being conducted on Levocetirizine (LTZ) is based in Kansas City, Missouri; however, there is 1 other location running a trial for this medication." - Anonymous Online Contributor

Unverified Answer

Are participants in this trial of age 18 years or older?

"In order for a patient to be included in this trial, they must be aged between 6 and 17 years old. Out of the 327 similar studies, 119 are for patients under 18 and 204 are for patients over 65." - Anonymous Online Contributor

Unverified Answer

For what common ailment is Levocetirizine (LTZ) most often prescribed?

"Levocetirizine is most commonly used to treat seasonal allergies, but it can also alleviate conditions like catarrh, chronic idiopathic urticaria, and nasal congestion." - Anonymous Online Contributor

Unverified Answer

Are people still being signed up for this experiment?

"Yes, this information is accurate. The study was posted on April 28th, 2021 and updated on April 26th, 2022." - Anonymous Online Contributor

Unverified Answer

What other similar medical trials have preceded this one?

"Clinical research for Levocetirizine (LTZ) started in 2009. The first large-scale study was sponsored by HK inno.N Corporation and had 100 participants. After the success of the initial Phase 4 trial, there are now 2 active studies being conducted across 1 city and 1 nation." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.