108 Participants NeededMy employer runs this trial

Radiation Boost for Spine Cancer

(OPTIMAL Trial)

No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

Spine SBRT is considered a standard of care for the treatment of spinal metastases. Compared to conventional radiation therapy, spine SBRT delivers high doses of radiation to the affected areas to the spinal metastases.

This study is interested in seeing whether an additional 'boost' of radiation, delivered to the affected area in the spine, will result in better long-term control of the tumor; help reduce pain; and reduce long-term side effects of radiation therapy.

Are You a Good Fit for This Trial?

Inclusion Criteria

I have been diagnosed with, or am strongly suspected to have, a solid tumor cancer.
I have spinal cancer that has spread near my spine and need SBRT treatment.
I am able to care for myself and do daily activities.
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Radiation

Participants receive a radiation boost to their spinal metastases

6-8 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Radiation Boost

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Radiation BoostExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Sunnybrook Health Sciences Centre

Lead Sponsor

Trials
693
Recruited
1,569,000+