Sage for Borderline Personality Disorder
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new therapy called Sage, designed for individuals with borderline personality disorder (BPD) and their partners. Sage aims to improve BPD symptoms, reduce relationship conflict, and enhance partner mental health. The study compares the effectiveness of Sage to standard supportive individual therapy (SIP). Couples where one partner has BPD and experiences frequent relationship conflicts might be well-suited for this trial. Participants should live in Ontario, have regular internet access, and be willing to engage in therapy sessions together. As a Phase 2 trial, this research measures the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to important advancements in BPD therapy.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. However, if you are currently receiving an empirically-supported BPD treatment, you must pause it during the active treatment phase of the study.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that the Sage treatment for borderline personality disorder (BPD) is under careful study to ensure safety and effectiveness. An earlier study tested Sage with individuals who have BPD and their partners, and the results suggested it is safe and may be beneficial.
The Sage treatment prioritizes safety by focusing on reducing harmful behaviors, such as suicide attempts, making safety a key part of its design. Although more detailed safety information from larger studies is needed, these early results are encouraging. Sage aims to improve emotional and relationship health for people with BPD and their partners, potentially making it a comprehensive treatment option.
Overall, Sage appears to be a well-designed therapy with safety measures in place. However, further research is necessary to fully confirm its safety.1234Why are researchers excited about this trial's treatments?
Researchers are excited about the Sage treatment for Borderline Personality Disorder (BPD) because it combines psychotherapy with a focus on improving relationship dynamics, which is a novel approach. Unlike traditional therapies like Dialectical Behavior Therapy (DBT) or Cognitive Behavioral Therapy (CBT), which primarily focus on the individual's symptoms, Sage aims to enhance relationship functioning alongside treating BPD. This dual focus has the potential to address both the personal and interpersonal challenges faced by individuals with BPD, potentially leading to more comprehensive and lasting improvements.
What evidence suggests that this trial's treatments could be effective for borderline personality disorder?
Research has shown that Sage, one of the therapies studied in this trial, may help treat borderline personality disorder (BPD). In a previous study, participants experienced improvements in BPD symptom severity, suicidal thoughts, and self-harming behavior. About half of the couples reported less conflict in their relationships. Sage addresses emotional and relationship issues, which are crucial for managing BPD. This approach could benefit both individuals with BPD and their partners by addressing mental health together. Participants in this trial will receive either Sage or Supportive Individual Psychotherapy (SIP), which involves individual sessions for both the person with BPD and their partner.14567
Are You a Good Fit for This Trial?
This trial is for couples where one partner has been diagnosed with Borderline Personality Disorder (BPD) and meets the full criteria. Both partners must be at least 19 years old, live in Ontario without plans to leave during the study, speak English fluently, consent to participate and have their sessions recorded, and have regular internet access from a private location.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive 12 sessions of either Sage couple psychotherapy or Supportive Individual Psychotherapy (SIP)
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Sage
- Supportive Individual Psychotherapy
Trial Overview
The trial is testing Sage—a new 12-session conjoint intervention targeting BPD symptoms, relationship conflict, and partner mental health—against standard supportive individual psychotherapy (SIP). Couples will be randomly assigned to either treatment group and outcomes will be measured over time including follow-ups.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Immediately receives 12 sessions of a couple psychotherapy designed to treat borderline personality disorder (BPD) and enhances relationship functioning simultaneously.
Immediately receives 12 individual sessions each (12 for people with borderline personality disorder (BPD), 12 for partners) of Supportive Individual Psychotherapy (SIP).
Find a Clinic Near You
Who Is Running the Clinical Trial?
York University
Lead Sponsor
University of Windsor
Collaborator
Centre for Addiction and Mental Health
Collaborator
Toronto Metropolitan University
Collaborator
Kennesaw State University
Collaborator
University of Winnipeg
Collaborator
The Sashbear Foundation
Collaborator
Citations
A case series of sage: a new couple-based intervention for ...
The effectiveness of 6 versus 12-months of dialectical behaviour therapy for borderline personality disorder: the feasibility of a shorter ...
Testing Interventions for Borderline Personality Disorder.
The study will examine if Sage is more efficacious than SIP in improving BPD symptoms (primary outcome), as well as relationship conflict and partner mental ...
Systematic Review of the Effectiveness and Experiences ...
Compared to women, men were less likely to access treatment for BPD or find treatment helpful. Our findings demonstrated the potential efficacy ...
A Novel Conjoint Intervention for Suicidal and Self-Injuring ...
Sage has three phases: safety, communication/emotion regulation, and beliefs. •. Sage may optimize, expedite, and expand access to intervention for BPD and SOs.
5.
researchgate.net
researchgate.net/publication/377357522_A_case_series_of_sage_a_new_couple-based_intervention_for_borderline_personality_disorder(PDF) A case series of sage: a new couple-based ...
Improvements were generally demonstrated in BPD severity, suicidal ideation, and suicidal behavior/self-injury. Half of dyads exhibited improvements in conflict ...
Borderline Personality Disorder - Sage Knowledge
Characteristics of borderline personality disorder include emotional instability with wide mood swings, instability in relationships, self-injurious behaviors, ...
A couple therapy for borderline personality disorder
The current paper presents the primary and secondary outcomes from an uncontrolled trial of Sage, a manualized conjoint treatment for people with BPD and their ...
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