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Dextrose Injections for Knee Osteoarthritis
Study Summary
This trial is testing whether an ultrasound-guided dextrose injection can improve symptoms of knee OA when done every 6 weeks, and whether it is more effective than doing the injection every 3 weeks.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I have diabetes.I have had knee pain of 4 or more on a scale of 0-10 for the last 3 months.I use opioid medication every day.I have had a total knee replacement.You have an allergy or intolerance to the study medication or to corn.A radiologist found knee osteoarthritis on my X-ray taken in the last 3 years.I have not had a knee injection in the last 3 months.I have had knee pain of 4 or more on a scale of 0-10 for the last 3 months.I have had knee prolotherapy or similar treatments before.I have been diagnosed with knee osteoarthritis.I have inflammation or arthritis in my knee due to conditions like RA or gout.I am on blood thinners.
- Group 1: Four injections of placebo
- Group 2: One injection of DPT and three injections of placebo
- Group 3: Two injections of DPT and two injections of placebo
- Group 4: Four injections of DPT
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the age restriction for participation in this trial extend beyond 55 years?
"This research is seeking study participants aged between 40 and 80 years."
Has Dextrose prolotherapy (DPT) been greenlighted by the FDA?
"Due to the limited amount of evidence backing up its effectiveness, Dextrose Prolotherapy (DPT) was scored a 2 - indicating moderate safety profiles."
How many participants are being included in the research endeavor?
"Affirmative. The information hosted on clinicaltrials.gov asserts that this health-related study is actively recruiting volunteers; it was first announced April 10th 2022 and last updated 21 days later. A total of 160 participants are sought at one medical centre."
Do I meet the criteria to partake in this medical research?
"To be eligible to take part in this study, potential participants must aged between 40 and 80 years old and have arthrosis-related knee pain that is moderate or severe (scored ≥ 4 on a 0–10 point numeric rating scale) for more than 3 months. A total of 160 volunteers are needed."
Is there still an opportunity to join the study at this point in time?
"Referring to the details available on clinicaltrials.gov, it appears that this medical trial is open for enrollment with a commencement date of April 10th 2022 and has been recently updated as of April 21st 2022."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
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