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Radiation Therapy for Spinal Cancer
Study Summary
This trial compares 3 types of radiation therapy for cancer that has spread to the spine. EBRT and SBRT deliver radiation to the body from outside or target small areas respectively. Patients are randomly assigned to one of the 3 radiation therapies.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- The origin of my cancer is unknown.I am not considered a candidate for SBRT according to my radiation oncologist.I have nerve issues due to cancer in my spine.My spine treatment involves more than 3 backbones in a row.I do not have any severe illnesses that could interfere with the study.I have had spine surgery in the area targeted for radiation, but not just a biopsy.I am over 18 years old.My worst pain level is less than 2 on a scale of 0 to 10.I am not pregnant or nursing, as radiation therapy could be harmful.I have had radiation therapy in the same area where SBRT is planned.I've had targeted radiation therapy that overlaps with my current treatment area.My doctor estimates I have 3 months or less to live.I am a candidate for spine radiation therapy as per my oncologist.I can understand and am willing to sign the consent form.I do not plan to change my pain medication on the day I start SBRT.My spine is unstable due to cancer, as measured by a specific score.My cancer diagnosis and spinal metastasis are confirmed by tests.I have not had any previous treatments, including radiation, for my condition.
- Group 1: Conventional EBRT
- Group 2: High dose SBRT
- Group 3: Standard dose SBRT
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is enrollment open to participants in this clinical experiment presently?
"Clinicaltrials.gov records indicate that this study is no longer accepting participants, as the trial's first posting was on January 1st 2023 and its most recent amendments were made on November 8th 2022. However, 2928 other clinical trials are currently enrolling patients."
How can patients be assured of safety when undergoing High dose SBRT?
"Although efficacy data is yet to be published, the High dose SBRT has been assessed as a 2 on our team's scale of 1-3 for safety due to Phase 2 trial results."
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