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200 Participants NeededMy employer runs this trial

Belantamab Mafodotin + Standard Care for Multiple Myeloma

Recruiting at 5 trial locations
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: GlaxoSmithKline
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is for adults with multiple myeloma (a type of blood cancer) that has come back after being treated earlier or isn't responding to the current treatment.

The main goal is to find out if the study drug, belantamab mafodotin, given less often (on an extended schedule) with other cancer medicines, can still treat the cancer effectively while causing fewer side effects, especially those affecting the eyes. The study will also look at how well the treatment works overall and how safe it is when administered to the participants.

Are You a Good Fit for This Trial?

Inclusion Criteria

I have taken lenalidomide for at least 2 cycles in a previous treatment.
I have at least one tumor or lesion that can be measured.
Participants must meet contraceptive requirements as per local regulations
See 8 more

Exclusion Criteria

I have not taken pomalidomide before and am not intolerant to it.
I do not have active plasma cell leukemia.
I have not had any other invasive cancers besides multiple myeloma under allowed conditions.
See 20 more

What Are the Treatments Tested in This Trial?

Interventions

  • Belantamab Mafodotin

How Is the Trial Designed?

3

Treatment groups

Experimental Treatment

Group I: Belantamab mafodotin + Pomalidomide + Dexamethasone (BPd)Experimental Treatment3 Interventions
Group II: Belantamab mafodotin + Carfilzomib + dexamethasone (BKd)Experimental Treatment3 Interventions
Group III: Belantamab mafodotin + Bortezomib + Dexamethasone (BVd)Experimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

GlaxoSmithKline

Lead Sponsor

Trials
4,834
Recruited
8,389,000+
Headquarters
London, UK
Known For
Vaccines & Medicines
Top Products
**Advair (salmeterol, fluticasone propionate)**, **Shingrix (shingles vaccine)**, **Augmentin (amoxicillin/clavulanate potassium)**, **Ventolin (salbutamol sulfate)
Dame Emma Walmsley profile image

Dame Emma Walmsley

GlaxoSmithKline

Chief Executive Officer since 2017

MA in Classics and Modern Languages from Oxford University

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Dr. Hal Barron

GlaxoSmithKline

Chief Medical Officer since 2018

MD from Harvard Medical School

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