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Treatment (nivolumab and cabozantinib) for Hypopharyngeal Cancer
Study Summary
This trialstudies combining two drugs to treat melanoma and head/neck cancer that has spread to other parts of the body. It also looks at biomarkers in tumors to see how well treatment works.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
To what ailments is the treatment of nivolumab and cabozantinib most commonly applied?
"Nivolumab and cabozantinib are treatments traditionally used for malignant neoplasms. But, they can be prescribed to patients with unresectable melanoma, squamous cell carcinoma, or metastatic esophageal adenocarcinoma if their symptoms warrant it."
What evidence is there to suggest that the use of nivolumab and cabozantinib carries no risk for those receiving it?
"The safety of the nivolumab and cabozantinib combination therapy was deemed a 2 because, despite there being some evidence supporting its security profile, no data confirming efficacy has been presented."
Is this study precedent-setting in its methodology?
"Treatment (nivolumab and cabozantinib) has been the subject of extensive clinical research since its initial trial in 2012, sponsored by Exelixis. Following a successful Phase 1 study involving 86 patients, it was progressed to Phase 2 approval. In total, 794 trials are currently underway across 53 nations and 2553 cities."
What is the maximum capacity of participants for this experiment?
"Affirmative. Clinicaltrials.gov displays evidence that this clinical trial, initially put up on October 14th 2022, is actively enrolling patients. Around 150 individuals are being recruited from 28 distinct medical sites."
Are there slots available for participation in this scientific experiment?
"Accurate. According to records located on clinicaltrials.gov, this trial is accepting participants and was first posted on October 14th 2022 with the latest update occurring November 24th of the same year."
How many facilities are administering this experiment?
"This clinical trial is inviting patients across 28 sites, including Illinois CancerCare-Ottawa Clinic in Ottawa, McFarland Clinic PC - Ames in Ames, and McFarland Clinic PC-Jefferson in Jefferson."
Have any further investigations been conducted utilizing nivolumab and cabozantinib?
"At present, 794 clinical trials concerning Treatment (nivolumab and cabozantinib) are in progress. 90 of these studies have reached Phase 3 with the majority taking place in Zürich, BE. However, 43554 sites worldwide are running trials for this particular intervention."
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