Radiation Therapy for Follicular Lymphoma
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to determine the optimal radiation dose fractionation regimen for low grade follicular lymphoma.It is hypothesized that the complete response rate with the use of 12 Gy in 6 daily fractions is 80% (10% total width of the confidence interval) at 3 months.This phase II study will evaluate whether an intermediate dose for follicular lymphoma is associated with excellent response rates while minimizing acute and late toxicity.
Who Is on the Research Team?
May Tsao, MD
Principal Investigator
Sunnybrook Health Sciences Centre
Are You a Good Fit for This Trial?
This trial is for adults over 18 with low-grade (grade 1-2) follicular lymphoma that hasn't been treated with radiation before. It's for those who need radiation for local disease control, have non-bulky targets under 7cm, and can consent to treatment. Pregnant individuals or those on systemic therapy for lymphoma within the last 3 months are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Radiation
Participants receive 12 Gy in 6 daily fractions for low grade follicular lymphoma
Follow-up
Participants are monitored for response and toxicity at 1 month and 3 months post-radiation
What Are the Treatments Tested in This Trial?
Interventions
- 12 Gy in 6 daily fractions
Find a Clinic Near You
Who Is Running the Clinical Trial?
Sunnybrook Health Sciences Centre
Lead Sponsor