CD388 Injection for Flu Prevention
(NAVIGATE Trial)
Trial Summary
Do I have to stop taking my current medications to join the trial?
The trial information does not specify if you need to stop taking your current medications. However, you should discuss your medications with the study team to ensure they don't interfere with the trial.
What data supports the effectiveness of the drug CD388 Injection for flu prevention?
Research on similar treatments shows that using adjuvants (substances that enhance the body's immune response to an antigen) can improve the effectiveness of flu vaccines. For example, the use of adjuvants like CpG 1018 in vaccines has been shown to provide strong protection against flu in animal studies.12345
How is the drug CD388 unique for flu prevention?
What is the purpose of this trial?
The purpose of this study is to evaluate the effectiveness of CD388 in preventing symptomatic laboratory-confirmed influenza infections, as compared to placebo, and to select a dose of CD388 that is effective in preventing the same, when administered as a single dose via 3 subcutaneous (SQ) injections to adult participants in stable health, and to evaluate the safety and tolerability of CD388, as compared to placebo.
Research Team
Nicole Davarpanah, MD, JD
Principal Investigator
Cidara Therapeutics Inc.
Eligibility Criteria
This trial is for healthy adults who are not at high risk of complications from the flu. Participants will receive a single dose of CD388 or a placebo to test its effectiveness in preventing influenza.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single dose of CD388 via 3 subcutaneous injections
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- CD388
Find a Clinic Near You
Who Is Running the Clinical Trial?
Cidara Therapeutics Inc.
Lead Sponsor