Low-Dose Naltrexone for Chronic Fatigue Syndrome

JY
Overseen ByJarred Younger, PhD
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: University of Alabama at Birmingham
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This exploratory clinical trial tests low-dose naltrexone (LDN) for the treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A remote trial approach is used, with eligibility open to the entire U.S.

Who Is on the Research Team?

JY

Jarred Younger, PhD

Principal Investigator

University of Alabama at Birmingham

Are You a Good Fit for This Trial?

This trial is for individuals across the U.S. with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Specific eligibility criteria are not provided, but typically these would include age range, disease severity, and other health conditions.

Inclusion Criteria

Living in the United States
I am between 18 and 65 years old.
Meets ME-ICC criteria

Exclusion Criteria

I am currently using opioid pain medication.
Abnormal complete blood count
A1C > 9.0%
See 6 more

What Are the Treatments Tested in This Trial?

Interventions

  • Low-Dose Naltrexone

Trial Overview

The study explores different doses of Low-Dose Naltrexone (LDN) to treat ME/CFS. Participants will receive one of four possible doses: 1.5mg, 3.0mg, 4.5mg or 6.0mg to determine which works best.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Participants Receiving Low-Dose NaltrexoneExperimental Treatment4 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Alabama at Birmingham

Lead Sponsor

Trials
1,677
Recruited
2,458,000+