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Stem Cell Transplant for Crohn's Disease
Study Summary
This trial is testing whether high-dose chemotherapy followed by infusion of autologous CD34-selected peripheral blood stem cells is safe and effective in treating Crohn's disease.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have severe Crohn's disease not responding to treatment and might need a stem cell transplant.I am a female over 10 or have started my periods, not pregnant, and agree to use birth control.I have responded to treatment without needing steroids continuously.I have not had a severely swollen colon or a tear in my intestine.I am between 10 and 60 years old.I haven't been treated with standard doses of 6-MP, 5-ASA, or metronidazole.I have not had an infection within two weeks before my intense cancer treatment.
- Group 1: 1
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could I potentially qualify to participate in this experiment?
"To be eligible for inclusion in this experiment, participants must have ileocolitis and fall within the 10 to 60 age range. There are 20 positions available at present."
Is there an opportunity to join this clinical experiment at present?
"According to the data posted on clinicaltrials.gov, this medical experiment is currently enlisting participants and has been since June 26th 2012 with its most recent update occurring February 9th 2022."
What conditions is autologous CD34-selected peripheral blood stem cells transplant traditionally used to treat?
"Autologous CD34-selected peripheral blood stem cells transplant can be utilized to treat multiple sclerosis, polyangium and b-cell lymphomas."
What findings have been revealed in other investigations regarding autologous CD34-selected peripheral blood stem cell transplant?
"Currently, 1272 medical trials are underway to assess the efficacy of autologous CD34-selected peripheral blood stem cells transplant. Of those studies in progress, 249 have entered Phase 3. While many experiments for this treatment originate from Philadelphia, Pennsylvania, 39401 other sites worldwide are conducting research as well."
Is eligibility for the experiment open to individuals who are older than fifty-five?
"This clinical trial requires participants between the ages of 10 and 60. For those under 18, there are 451 trials available; for those over 65, 1198 trails exist."
How many participants has this trial enrolled thus far?
"Affirmative. Clinicaltrials.gov's records demonstrate that this clinical trial, which was first publicized on June 26th 2012, is currently recruiting individuals for the study. A total of 20 people must be recruited from 2 separate medical sites."
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