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Olanzapine and Mirtazapine for Weight Loss in Advanced Stage Cancer
Study Summary
This trial is comparing olanzapine to mirtazapine to see which is more effective in preventing weight loss and appetite loss in cancer patients.
- Anorexia Nervosa
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2008 Phase 4 trial • 25 Patients • NCT00001656Trial Design
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Who is running the clinical trial?
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- You have taken Marinol within two weeks before joining the study.You have lost more than 5% of your body weight over the last 3-6 months without trying to lose weight. This is not due to just not eating, and has not improved with standard nutrition advice and supplements for at least 2 weeks.You can still participate even if you are taking Dexamethasone.You are expected to live for at least 4 more months.
- Group 1: Olanzapine
- Group 2: Mirtazapine
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What medical conditions does Olanzapine commonly help to alleviate?
"Olanzapine is not only used to treat post traumatic stress disorder (PTSD), but also panic attacks, major depressive disorder (MDD), and acute agitation."
What is the United States Federal Drug Administration's opinion on Olanzapine?
"While Phase 2 trials don't have the same amount of data supporting efficacy, there is enough information to suggest that Olanzapine is safe."
What other trials are similar to this one?
"Zyprexa (olanzapine) was first studied in 2007 by Eli Lilly and Company. 20 patients were involved in the initial clinical trial which ultimately led to drug approval. 28 active studies are currently ongoing across 11 countries and 407 cities."
Are there any current openings for individuals in this trial?
"The clinical trial in question is no longer recruiting patients, as indicated by the website clinicaltrials.gov. This particular study was first posted on 1/20/2022 and updated for the last time on 7/25/2022. However, 419 other trials are still looking for patients to enroll."
Are there other scientific investigations that have included Olanzapine in their research?
"Olanzapine is being trialed in 28 different ongoing clinical studies, 7 of which are Phase 3 trials. The majority of the locations for these trials are based in Wheat Ridge, Colorado; however, there are a total of 738 sites running Olanzapine trials."
How many test subjects are involved in this research project?
"This trial is no longer looking for new patients to enroll. It was originally posted on 1/20/2022, with the most recent edit on 7/25/2022. However, there are other clinical trials - 391 related to anorexia and 28 involving Olanzapine - that are still recruiting participants."
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